Question: I have had long-term reflux and have even had fundoplication, which is still in place, but only worked for 2 years. As well as the modern treatments (I take Lansoprazole, but have been prescribed all of the PPI's) up to 2 years ago I felt really ill most days, coupled with severe stomach pain, vision disorder, dizziness, breathlessness. At worst I was bedridden, sometimes I would take myself off the road because my vision was being affected. I was treated with all the second line drugs, such as amitriptyline, dosolupin, baclofen, in fact a whole line other anti-depressants. I couldn't tolerate any of them and none of them made me feel one bit better. Through being so unwell I asked for Diazepam on a couple of occasions and apart from calming me down, they also seemed to help with the symptons. 2 years I started buying Alprazolam to take on a daily basis, though with a fluctuating dose. Maintenance of 2-4 x1mg tabs, up to 6-8mg when my stomach really flaired up. I have not been unwell in the last 2 years. Is Xanax seen as a valid treatment? I believe I have not only endured reflux for most of my life, but increasingly also severe stomach spasm. The alprazolam has made a big difference to me personally, but I cannot find much literature to support its use over the anti-depressants. I am aware of the dependancy issues, though I am pleased that I have not had to increase the dose to get the same effect. I would like my Doctor to try me on other anti-anxiety drugs, prescribable on the UK NHS. I am aware Xanax is not prescribable in the UK, but I feel ANY of the other benzodiazepines would be just as effective. I have always had a poor gut and have been diagnosed with diverticulosus. The pains have increased over recent years and are now quite troublesome. The alprazolam helps, but I also wonder if there is any evidence of alprazolam actually causing intestinal pain? I would be interested in your response (and apologies for any typo's). Many thanks.