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Greetings, Dr. Sharka. Last Time I Discussed With You Taking

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Posted on Sun, 22 Nov 2020
Question: Greetings, Dr. Sharka. Last time I discussed with you taking Cozaar 100 mg with a Potassium/Magnesium supplement that is very helpful to me (3x 300 mg each). I discontinued the supplement until now, after my outpatient breast surgery for Paget's Disease. I requested my GP change the BP medication so that I can resume my supplement. She has now started me on Lisinopril 10 mg once a day for at least 1 month so that I can take my supplement. She told me that this would be no problem with the potassium in the supplement. Is there some kind of difference between Cozaar and Lisinopril in this issue? Also, why would someone use one or the other for mildly to moderately elevated blood pressure? Thank you.
doctor
Answered by Dr. Ilir Sharka (3 hours later)
Brief Answer:
I would explain as follows:

Detailed Answer:
Hello again, dear David!

Welcome back on this platform!

I passed carefully through your recent medical history and let me explain that Lisinopril and Cozaar have similar behavior regarding blood potassium level. They both act on renin-angiotensin-aldosterone system by blocking aldosterone effects with subsequent potassium retention.

Coming to this point, I would advise to be careful when using concomitantly Lisinopril and potassium supplements. They may lead to elevated blood potassium levels with adverse effects like muscle weakness, cardiac arrhythmias, etc. In case you notice any unusually new symptoms, it would be necessary to check your blood potassium level and if hyperkalemia is confirmed, stopping potassium supplements temporarily would be required.

Another alternative would be to use a calcium channel blocker (Amlodipine, Lercanidipine, etc.) instead of Lisinopril; which appear safe regarding any adverse effects on potassium levels. You could discuss with your GP on this issue.

Hope you will find this answer helpful!

Let me know in case of any further question.

Kind regards,

Dr. Ilri Sharka
cardiologist
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Ilir Sharka (8 minutes later)
Thank you . Does it matter if the Lisinopril is only 10 mg? My doctor didn't seem concerned at least dt that dosage
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Follow up: Dr. Ilir Sharka (1 minute later)
Anyway, what would be the difference between Cozaar and Lisinopril in general, and where the first is 100mg and the other 10mg ?
doctor
Answered by Dr. Ilir Sharka (2 minutes later)
Brief Answer:
Opinion as follows:

Detailed Answer:
Hello again!

Lisinopril 10 mg is considered a low dose and would not have any great impact on potassium. So, your doctor is right when considering this issue.

Greetings,

Dr. Iliri
Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Ilir Sharka

Cardiologist

Practicing since :2001

Answered : 9539 Questions

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Greetings, Dr. Sharka. Last Time I Discussed With You Taking

Brief Answer: I would explain as follows: Detailed Answer: Hello again, dear David! Welcome back on this platform! I passed carefully through your recent medical history and let me explain that Lisinopril and Cozaar have similar behavior regarding blood potassium level. They both act on renin-angiotensin-aldosterone system by blocking aldosterone effects with subsequent potassium retention. Coming to this point, I would advise to be careful when using concomitantly Lisinopril and potassium supplements. They may lead to elevated blood potassium levels with adverse effects like muscle weakness, cardiac arrhythmias, etc. In case you notice any unusually new symptoms, it would be necessary to check your blood potassium level and if hyperkalemia is confirmed, stopping potassium supplements temporarily would be required. Another alternative would be to use a calcium channel blocker (Amlodipine, Lercanidipine, etc.) instead of Lisinopril; which appear safe regarding any adverse effects on potassium levels. You could discuss with your GP on this issue. Hope you will find this answer helpful! Let me know in case of any further question. Kind regards, Dr. Ilri Sharka cardiologist