Have Crohn's Disease. Take Remicade. CRP And Creatinine Levels Are High. What Is Causing The Problem?
Question: I have crohn's disease and am not feeling well. I take remicade and my creatinine is elevated and so is my CRP. Trying to determine if I am experiencing a flare from the chron's or if the remicade is causing my problem.
Brief Answer:
Inflammatory evidence
Detailed Answer:
Dear XXXXXXX
Thanks for the question. It is extremely rare for infliximab to cause kidney failure; however, when liver or kidney function is impaired, the dose should be adjusted appropriately. With such a potent biologic agent, your CRP levels, although non-specific, should be within normal limits, so if significantly elevated may mean disease activity and the need to touch base with your treating GI or rheumatology specialist.
Yours truly,
Dr Brenes-Salazar MD
Mayo Clinic MN
Inflammatory evidence
Detailed Answer:
Dear XXXXXXX
Thanks for the question. It is extremely rare for infliximab to cause kidney failure; however, when liver or kidney function is impaired, the dose should be adjusted appropriately. With such a potent biologic agent, your CRP levels, although non-specific, should be within normal limits, so if significantly elevated may mean disease activity and the need to touch base with your treating GI or rheumatology specialist.
Yours truly,
Dr Brenes-Salazar MD
Mayo Clinic MN
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
This is very helpful. Thank you.
Brief Answer:
Welcome
Detailed Answer:
Very welcome XXXXXXX
Let me know if I can be of further assistance.
Dr Brenes-Salazar MD
Welcome
Detailed Answer:
Very welcome XXXXXXX
Let me know if I can be of further assistance.
Dr Brenes-Salazar MD
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Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar