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Have Low Globulin And High Ag Ratio. What Should I Do?

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Posted on Mon, 31 Dec 2012
Question: I have low globulin 1.9 , and ag ratio 2.6 high
doctor
Answered by Dr. Das Arindam (1 hour later)
Hello,

Thank you for posting a query.

Firstly, in serum, there are two main proteins albumin and globulin. Normally, albumin constitute near about 60 percent of total protein. So, albumin is the main protein of concern. Its lower level indicates many disease including kidney and liver psthology.

Clinically, we take 1.8 as lower normal value for globulin. According to this, your globulin level is just more than the lower value.

Normally albumin : globulin ratio is more than 1.5. In your case, it is 2.6. It is a very good indicator of serum protein balance. Higher value rules out any abnormality regarding serum protein.

So, there is no problem in your report. But it should be correlated clinically. Consult with your treating doctor about this.

Hope this information suffices. Let me know if you have any more question.

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Das Arindam (10 hours later)
My albumin was 4.9
So is that normal
doctor
Answered by Dr. Das Arindam (34 minutes later)
Hello,
Thank you for writing back.

Yes, the albumin is within normal limit.

Regards.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Das Arindam

General & Family Physician

Practicing since :2008

Answered : 1416 Questions

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Have Low Globulin And High Ag Ratio. What Should I Do?

Hello,

Thank you for posting a query.

Firstly, in serum, there are two main proteins albumin and globulin. Normally, albumin constitute near about 60 percent of total protein. So, albumin is the main protein of concern. Its lower level indicates many disease including kidney and liver psthology.

Clinically, we take 1.8 as lower normal value for globulin. According to this, your globulin level is just more than the lower value.

Normally albumin : globulin ratio is more than 1.5. In your case, it is 2.6. It is a very good indicator of serum protein balance. Higher value rules out any abnormality regarding serum protein.

So, there is no problem in your report. But it should be correlated clinically. Consult with your treating doctor about this.

Hope this information suffices. Let me know if you have any more question.

Regards.