
Have Low Grade Fever, Joint Pain, Sore Breast, Swollen Lymph Node Around Neck. Proper Diagnosis?

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You are a 54 year old other wise healthy female, with history of hysterectomy about 33 years back and cardiac stunting three times in last 6 years. You have been feeling flu like symptoms, low grade fever, body aches, joint pains in hands, hips, back, neck. Also breasts are painful. You are also having change in sleep pattern. Tiredness is also there. Lymphnodes appear to be swollen. Doctors are not checking seriously.
I would like to tell you that you have multiple system complaints and as you have said doctors could not find some serious problem. These type of symptoms may occur with following possibilities-
- One possibility is low hemoglobin. Although it can be easily ignored but low hemoglobin and anaemia is one of important cause of such type of symptoms. I will advise you to to get your Hemoglobin, Vitamin B12 levels checked.
- Other possibility may be Mild depression. It may occur in hypothyroid states also. In both cases such type of symptoms are seen. These type of symptoms are called as somatic symptoms. You should get your thyroid function tests done to rule out hypothyroidism.
- Other thing that may be possibility is Chronic Fatigue Syndrome. Possibility of this disease is very high in your case. It is almost similar to fibromyalgia. Lymph node swelling, tiredness, multiple pains, hot flushes, sleep problems etc are seen. Most common medicines to relieve pain as NSAID like ibuprofen are used for pain relief. Medicines like Duloxetine, Milnacipran etc are used for chronic relief of symptoms. I will advise you to please visit a good Doctor for proper evaluation and opinion regarding such symptoms.
Hope I cleared your query, If you have more questions you can ask again.
Thanks
Dr. Seikhoo Bishnoi, MD
(Consultant Psychiatrist)


Again, thank you so much for helping.
XXXXXX
Chronic Fatigue Syndrome is a diagnosis of exclusion. There are no definite tests for this. But once all other possibilities are ruled out then we can go for this diagnosis.
Just to summarize the diagnostic work up-
Total Haemogram (especially for Hemoglobin)
Vitamin B 12 levels (normal is 300-900 but it should be around >450 in you)
Folate levels (low folate common in females)
Thyroid function tests (T3/T4 in lower range and TSH in higher range)
Serum Cortisol levels, and if they come on lower side then go for DST (dexamethasone suppression test) for any glucocorticoid related stress symptoms.
Go for these investigations and if they come normal only then we can think of CFS.
One thing I missed in my last answer is Hot Flushes in pre and perimenopausal females. Due to hormonal changes such type of symptoms may be seen. For such symptoms most of Gynecologists advocate hormone therapy. But hormone therapy has a lot of side effects. I personally prefer to start medicines like Duloxetine and Fluoxetine for this, they control such symptoms easily.
As you are on blood thinners and aspirin I would not advise you to take Ibuprofen. But for control of pain symptoms and other somatic symptoms you can take Duloxetine which is safe with aspirin also and control pain effectively.
Take diet XXXXXXX in Vitamin B12 like animal foods milk, eggs, and if you can take then meat.
Hope I cleared your doubt, If you have more questions you can ask again. If satisfied with answer please review.
Thanks
Dr. Seikhoo Bishnoi, MD

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