
Hello, I Am Trying To Get Some Second Opinion For

I am trying to get some second opinion for my father's ischemic stroke. He (64 years) suffered the stroke on 10 days ago. Lost control over his right hand, leg and speech. He was administered the clot removal injection (tPA?) after around 2 hrs 45 mins. Soon after that he regained control over his right leg and right arm. But continued to struggle gripping anything in his right fist and struggled to speak. He spoke his first words 3 days after the stroke. He was discharged from the hospital with the following medications (until further review):
1) Eliquis (Apixaban)
2) Ecospirin (Aspirin)
3) Telmisartan
4) Strocit (Citicoline)
5) Rosuvastatin
He is currently doing speech therapy and physio therapy for this right hand strength. Right hand is improving well, he was able to write with it yesterday. Speech though is improving at a slow pace. Majority of his talk is garbled words and slurred speech. But compared to a week back he can pronounce and say many words and phrases.
Some historical context:
1) He had suffered a heart attack in the year 2001 and had angioplasty performed on him. He had been taking Aspirin medication since then.
2) In May of 2019 he had transient ischemic attack which laster for around 30 seconds. He lost speech during that process. But got it back right away. Back then too he got MRI and Carotid Doppler done. All the reports came back normal. So the doctor only increased his aspirin dosage and he went back to normal day today life.
Now here are my main questions:
1) Based on the attached reports , is the above treatment with medications the right one (Basically I need a second Neurologist's opinion on this. I trust our current Neurologist completely, but just for our peace of mind want a second opinion on this).
2) My main concern is about his speech recovery. Based on the CT or the MRI does it indicate any extensive damage to the language center in his brain? What should be the realistic expectations with respect to his speech coming back? Is regular speech therapy along with in home efforts by the family to get him to talk the right approach? Is there any other treatment that you would recommend.
I am attaching the MRI and CT scans done before and after the tPA injection and the discharge summary. If there is anything missing, please let me know. I can try to get that.
Thanks,
Kartik
Treatment is going on correct lines.
Detailed Answer:
Thank you for posting your query.
I am Dr Sudhir Kumar, Neurologist, and I would try my best to help you.
I have noted your father's clinical details and have seen the MRI and brain CT reports. Based on this, the diagnosis and treatment are going on along correct lines. He has received the best treatment (intravenous tPA) for the acute stroke.
The area affected by stroke is responsible for his speech impairment and we expect gradual improvement and recovery in speech over the next several weeks. The extent of recovery varies in different people, and it is difficult to predict the exact % of recovery in him. Yes, speech therapy is the mainstay. Piracetam tablets also help in speech recovery and you can discuss this with your neurologist.
My only question is regarding eliquis (apixaban). Apixaban is given for atrial fibrillation (a heart disease), which has not been mentioned in the discharge summary. So, when you meet your cardiologist/neurologist, please enquire about the indication of eliquis in him.
I hope my answer helps. Please get back if you have any follow up queries or if you require any additional information.
Wishing you good health,
Dr Sudhir Kumar MD (Internal Medicine), DM (Neurology) XXXXXXX Consultant Neurologist
Apollo Hospitals, XXXXXXX XXXXXXX
Click on this link to ask me a DIRECT QUERY: http://bit.ly/Dr-Sudhir-kumar
My BLOG: http://bestneurodoctor.blogspot.in



I have reviewed the attachments.
Detailed Answer:
Thank you for getting back.
I have reviewed the attachments- CT brain, MRI brain, Discharge summary and Holter report. Do you have any specific queries or concerns regarding them?
Dr Sudhir Kumar MD DM (Neurology)


Regarding Apixaban, the Neurologist suspected the clot might have come from the heart. I have attached the holter report which showed one incident of Ventricular tachycardia in the 24 hr window. But no Atrial Fibrillation. The cardiologist too felt it was ok to give apixaban.
With respect to your concern with the drug, do you feel its not adequate to stop future clots, due to absence of Atrial Fibrillation, or do you think its an overkill? Sorry for my ignorance, but if you could explain what your concern with Apixaban is?
Thanks,
Kartik

Apixaban is only indicated for atrial fibrillation.
Detailed Answer:
Apixaban is only indicated to prevent clot formation due to atrial fibrillation. As per the Holter report and discharge summary, there is no atrial fibrillation. So, it is not clear to me the reason for prescribing apixaban in this case.
If the cardiologist feels that the clot is formed in heart due to another heart disease (and not atrial fibrillation), then, warfarin is advised and not apixaban.
I hope my views are clear. However, the final opinion rests on the cardiologist as we are discussing about using apixaban for a heart disease.
Best wishes,
Dr Sudhir Kumar MD DM

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