Question: Hello doctor, yesterday i was thinking and so stressed and i did a pressure on my brain to continue thinking, my brain was overloaded and i felt a pain in my brain due to the overloading of thoughts and the stress and the press that i did on my brain to continue thinking. My question is: can this situation cause damage in DNA and mutation in genes cells of the brain in a direct way and cause brain cancer? And what happened is while this situation occured i had the idea popping up in brain saying that i will develop brain cancer because of this pressure to continue thinking that i did on my brain? Can the brain understand the thought and react to it with fear and cause DNA damages and genes mutation? Please doctor read my query carefully i know it is complicated a little bit but i need to know. I repeat: my situation is that i am worried because yesterday i was thinking a lot and i was stressed and my brain was full loaded with thoughts and me instead of stop thinking i did a pressure on my brain to continue thinking and by doing that i felt a pain in my brain. I am worried that this can cause DNA damage and genes mutation in my brain and cause brain cancer after that. So doctor i want to know does this situation can cause DNA damages and genes mutations and brain cancer aftet that? I mean this situation that i mentioned above (i was thinking a lot and i was stressed and my brain was full loaded with thoughts and me instead of stop thinking i did a pressure on my brain to continue thinking and by doing that i felt a pain in my brain). Can this cause DNA damages and genes mutations in a direct way and cause brain cancer in the future? Now i know that the immune system controls all the thing, but what if during this stress the imune system stop working or got weaken?? Can this happen doctor and mutations and damages occur? And can mutations in this case occur in a way that when the immune system get back to its normal status will not be able to fix the mutations??? Can this happen doctor?? I mean can brain cancer happen easily in a direct way like that or it's just more complicated that just this situation?? Please doctor i need a scientifical answer and what happen in the cells and DNA and genes level during this situation!! Sorry to make this too longue but really i am worried, and i need to know if i need MRI for my brain in the future or no? Waiting for your answer.