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Hi Doctor ,I Hope You Are Doing Well , I

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Posted on Sun, 30 Sep 2018
Question: Hi Doctor ,I hope you are doing well , I have had micopapillary carcinoma 2 years ago , my anti thyroglublin after Thyriodectomy was 74 and reduce to 3,8 and ref range is 0 to 41 after 8 month from surgery , and still stable up to last month but from last month up to now increased from 3.8 to 4,6 as the result of today and my Tsh level increased I can not control increased to be 6.6 iam taking eltroxin 200 every day , finally my Tg is still the same less than 0,04 suprresed and iam NED for 18 month now .... is that consider recurrence base on increase antithyroglublin ?? Please advise regards Ahmed
doctor
Answered by Dr. Mirjeta Guni (41 minutes later)
Brief Answer:
about thyroid carcinoma follow up;

Detailed Answer:
Hello and thank you for asking!
I have gone through your concern in details.

An increase of antithyroglobulin level from 3.8 to 4.6 is not significant.
Such small differences can be due to laboratory measurements.

As you may know, the target of the absence of the tumor residue is thyroglobulin under 1 with negative antibodies (no matter high how they are when they are still within the normal ranges). The absence of thyroid issue and lymph nodes an ultrasound and a negative scintiscan once a year.

So, you should not get worried about the antibodies but your physician will complete the other exams (once a year or occasionally) in order to be sure that everything is under control.

Best wishes,
Dr.Mirjeta


Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Mirjeta Guni (13 hours later)
Dear Doctor , thanks a lot for your reply. Do you think increase of AbTg from 3,8 to 4,6 within 45 days is not alarm for recurrence , I did the test in the same lab and other and it is the same . Last 3 weeks I did remove benign Granuloma from vocal cord , do u think any relation of this and TgAb? And do you think AbTg could comes back to the same level??thanks and best regards Ahmed
doctor
Answered by Dr. Mirjeta Guni (11 hours later)
Brief Answer:
About antiTg antibodies:

Detailed Answer:
Hi again,
AntiTg antibodies can hardly result exact the same value even if you check them within a few days.
There are slight insignificant changes, not to be taken intoconsideration.
There isn' t any known reason until now about the slight differences during the life time and even if they stay at these levels later on, it is not to get worried.
Best wishes,
Dr.Mirjeta
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Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Mirjeta Guni

Endocrinologist

Practicing since :2006

Answered : 2414 Questions

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Hi Doctor ,I Hope You Are Doing Well , I

Brief Answer: about thyroid carcinoma follow up; Detailed Answer: Hello and thank you for asking! I have gone through your concern in details. An increase of antithyroglobulin level from 3.8 to 4.6 is not significant. Such small differences can be due to laboratory measurements. As you may know, the target of the absence of the tumor residue is thyroglobulin under 1 with negative antibodies (no matter high how they are when they are still within the normal ranges). The absence of thyroid issue and lymph nodes an ultrasound and a negative scintiscan once a year. So, you should not get worried about the antibodies but your physician will complete the other exams (once a year or occasionally) in order to be sure that everything is under control. Best wishes, Dr.Mirjeta