Hi Dr. Kumar! Your Were Wonderful Helping Me In The
Presence of different variants, surgical excision would be wiser
Detailed Answer:
Hi
Thanks for posting the query. My sincere apologies for the delayed reply.
I have gone through the histopathology report thoroughly and my opinion is as below.
1. There has been mixed cellularity of the tissues examined associated with a low grade dysplasia. The dysplasia is due to the presence of abnormal cells, wherein, there are more immature cells and less mature cells belonging to the same epithelium.
2. As you have rightly pointed out that, there are two variants of papilloma seen in the histopathology. It would be wiser to get it excised completely, rather than waiting and watching.
3. Also, there is only mild dysplastic changes which is of low grade, the chances of papilloma turning out to become malignant is very remote. Once the lesion is excised completely, then, we would be able to confirm HPV.
Hope this answers your query; revert back to me for any follow up queries.
Regards
Dr. Naveen Kumar N
ENT and Head & Neck Surgeon
Presence of different variants, surgical excision would be wiser
Detailed Answer:
Hi
Thanks for posting the query. My sincere apologies for the delayed reply.
I have gone through the histopathology report thoroughly and my opinion is as below.
1. There has been mixed cellularity of the tissues examined associated with a low grade dysplasia. The dysplasia is due to the presence of abnormal cells, wherein, there are more immature cells and less mature cells belonging to the same epithelium.
2. As you have rightly pointed out that, there are two variants of papilloma seen in the histopathology. It would be wiser to get it excised completely, rather than waiting and watching.
3. Also, there is only mild dysplastic changes which is of low grade, the chances of papilloma turning out to become malignant is very remote. Once the lesion is excised completely, then, we would be able to confirm HPV.
Hope this answers your query; revert back to me for any follow up queries.
Regards
Dr. Naveen Kumar N
ENT and Head & Neck Surgeon
And two last questions (I promise!): would you say this papilloma is just a random occurrence in my body and I don’t necessarily need to worry about developing more? And would you say I shouldn’t worry too much about this, as my surgeon will ideally remove all of it and monitor me for reoccurrence?
Thank you again immensely!!
And two last questions (I promise!): would you say this papilloma is just a random occurrence in my body and I don’t necessarily need to worry about developing more? And would you say I shouldn’t worry too much about this, as my surgeon will ideally remove all of it and monitor me for reoccurrence?
Thank you again immensely!!
The chances of this lesion turning out to become malignant is almost nil
Detailed Answer:
Hi
Welcome back
1. can you tell me which two it appears to be...the inverted type and exophytic?
A: The biopsied lesion has both the elements of inverted and exophytic variants. Due to the presence of an inverted papilloma variant, there are minor dysplastic changes. Hence, I opined that it would be wiser for us to remove the lesion in total. If the papilloma were to be of the single variant such as the exophytic type, then, I would have recommended you to wait and watch.
The transformation of sinonasal papillomas into malignancy has been described with Inverted Papilloma and Oncocytic papillomas involving the sinuses, but not in Exophytic papillomas of the septum.
2. would you say this papilloma is just a random occurrence in my body and I don’t necessarily need to worry about developing more?
A: The mere presence of HPV may not be enough to support the viral etiology of these papillomas. Chronic inflammation and Chronic sinusitis have also been hypothesized as a precursor for the development of sinonasal papillomas. Hence, it could be a random occurrence in the nose and not related to any other papillomatous lesions in the body.
3. And would you say I shouldn’t worry too much about this, as my surgeon will ideally remove all of it and monitor me for reoccurrence?
A: Yes, removal of the lesion in total would get rid of you from this problem. And, the recurrence rate following the removal of this lesion is almost nil. Hence, do not worry about this issue. Be cheerful...
I wish you good health
Regards
Dr. Naveen Kumar N.
ENT and Head & Neck Surgeon
The chances of this lesion turning out to become malignant is almost nil
Detailed Answer:
Hi
Welcome back
1. can you tell me which two it appears to be...the inverted type and exophytic?
A: The biopsied lesion has both the elements of inverted and exophytic variants. Due to the presence of an inverted papilloma variant, there are minor dysplastic changes. Hence, I opined that it would be wiser for us to remove the lesion in total. If the papilloma were to be of the single variant such as the exophytic type, then, I would have recommended you to wait and watch.
The transformation of sinonasal papillomas into malignancy has been described with Inverted Papilloma and Oncocytic papillomas involving the sinuses, but not in Exophytic papillomas of the septum.
2. would you say this papilloma is just a random occurrence in my body and I don’t necessarily need to worry about developing more?
A: The mere presence of HPV may not be enough to support the viral etiology of these papillomas. Chronic inflammation and Chronic sinusitis have also been hypothesized as a precursor for the development of sinonasal papillomas. Hence, it could be a random occurrence in the nose and not related to any other papillomatous lesions in the body.
3. And would you say I shouldn’t worry too much about this, as my surgeon will ideally remove all of it and monitor me for reoccurrence?
A: Yes, removal of the lesion in total would get rid of you from this problem. And, the recurrence rate following the removal of this lesion is almost nil. Hence, do not worry about this issue. Be cheerful...
I wish you good health
Regards
Dr. Naveen Kumar N.
ENT and Head & Neck Surgeon
Wish you good XXXXXXX
Detailed Answer:
Hi
May the prayers and blessings of good health make you strong and healthy. God bless you.
warm regards
Dr. Naveen Kumar N
ENT and Head & Neck Surgeon
Wish you good XXXXXXX
Detailed Answer:
Hi
May the prayers and blessings of good health make you strong and healthy. God bless you.
warm regards
Dr. Naveen Kumar N
ENT and Head & Neck Surgeon
Answered by
Dr. Dr. Naveen Kumar Nanjasetty
Otolaryngologist / ENT Specialist
Practicing since :2001
Answered : 2543 Questions