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Hi I Had An Upper Endoscopy Yesterday. . I Have

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Posted on Thu, 28 Jan 2021
Question: Hi I had an upper endoscopy yesterday. . I have Gerd or reflux and my last one was 11 years ago along with colonoscopy and was perfectly normal. 11 years ago I went on the XXXXXXX diet and for the first time in my life I had reflux that sent me to the emergency room. I took acifex for a couple of years. That quit working and I went on dexilant 60mg. Took that for a couple of years and was able to get off that for around 6 years or more. During the stress and the pandemic ireflux started up again. I am on it now. My Question. I had a routine endoscopy and colonoscopy. I had 4 small polyps that my Dr. said were no big worry. She took biopsies of my esophhogus etc and thew only finding was chronic gastritis and z-line irregular at thr gastroesophageal juncion. Biopsied, Normal duodenum. I am now freaking out as to what all this means. Could you please explain. I know the biopsy will answer everything but that could be 10 days to 2 weeks.
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Follow up: Dr. Zubayer Alam (0 minute later)
Hi I had an upper endoscopy yesterday. . I have Gerd or reflux and my last one was 11 years ago along with colonoscopy and was perfectly normal. 11 years ago I went on the XXXXXXX diet and for the first time in my life I had reflux that sent me to the emergency room. I took acifex for a couple of years. That quit working and I went on dexilant 60mg. Took that for a couple of years and was able to get off that for around 6 years or more. During the stress and the pandemic ireflux started up again. I am on it now. My Question. I had a routine endoscopy and colonoscopy. I had 4 small polyps that my Dr. said were no big worry. She took biopsies of my esophhogus etc and thew only finding was chronic gastritis and z-line irregular at thr gastroesophageal juncion. Biopsied, Normal duodenum. I am now freaking out as to what all this means. Could you please explain. I know the biopsy will answer everything but that could be 10 days to 2 weeks.
doctor
Answered by Dr. Zubayer Alam (5 hours later)
Brief Answer:
Please see the detailed answer below.

Detailed Answer:
Hi,

Thank you for the query. I can understand your concern. According to your statement, you have been suffering from gastroesophageal reflux disease (GERD) for many years with an interval of few years.

Barrett's esophagus is a complication of long lasting GERD. Barrett's esophagus may be resulted from the repeated injuries due to the acidic fluids that caused by chronic severe acid reflux or GERD. In such cases, the normal squamous epithelium lining of oesophagus may change into specialized columnar epithelium due to chronic severe acid reflux. Thus, Barrett's oesophagus is formed. The specialized columnar lining of Barrett's oesophagus is more resistant to repeated injuries from acid reflux than the normal squamous lining.

The process of developing Barrett's oesophagus starts at the junction of stomach and oesophageal lining. The common border of this junction is known as z line. Again, an irregular z line is characterized by <1 cm columnar tongues that extend proximal to the gastroesophageal, a finding that has been reported in about 10-15% of the population undergoing upper endoscopy. <1 cm z line doesn't appear to be at risk of any cancerous conditions like adenocarcinoma.

If Barrett's oesophagus is detected while undergoing endoscopy, then biopsies are also done because, Barrett's oesophagus may turn into any cancerous conditions in few cases. So, biopsy should be done to exclude any cancerous conditions in case of Barrett's oesophagus.

So, don't be worried at all. Nothing has confirmed yet without Barrett's oesophagus in your case. Your biopsy report may show non cancerous conditions as in case of Barrett's oesophagus such type of changes can find while undergoing endoscopy.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Zubayer Alam, General And Family Physician,
Above answer was peer-reviewed by : Dr. Kampana
doctor
doctor
Answered by Dr. Zubayer Alam (0 minute later)
Brief Answer:
Please see the detailed answer below.

Detailed Answer:
Hi,

Thank you for the query. I can understand your concern. According to your statement, you have been suffering from gastroesophageal reflux disease (GERD) for many years with an interval of few years.

Barrett's esophagus is a complication of long lasting GERD. Barrett's esophagus may be resulted from the repeated injuries due to the acidic fluids that caused by chronic severe acid reflux or GERD. In such cases, the normal squamous epithelium lining of oesophagus may change into specialized columnar epithelium due to chronic severe acid reflux. Thus, Barrett's oesophagus is formed. The specialized columnar lining of Barrett's oesophagus is more resistant to repeated injuries from acid reflux than the normal squamous lining.

The process of developing Barrett's oesophagus starts at the junction of stomach and oesophageal lining. The common border of this junction is known as z line. Again, an irregular z line is characterized by <1 cm columnar tongues that extend proximal to the gastroesophageal, a finding that has been reported in about 10-15% of the population undergoing upper endoscopy. <1 cm z line doesn't appear to be at risk of any cancerous conditions like adenocarcinoma.

If Barrett's oesophagus is detected while undergoing endoscopy, then biopsies are also done because, Barrett's oesophagus may turn into any cancerous conditions in few cases. So, biopsy should be done to exclude any cancerous conditions in case of Barrett's oesophagus.

So, don't be worried at all. Nothing has confirmed yet without Barrett's oesophagus in your case. Your biopsy report may show non cancerous conditions as in case of Barrett's oesophagus such type of changes can find while undergoing endoscopy.

Take care. Hope I have answered your question. Let me know if I can assist you further.

Regards,
Dr. Zubayer Alam, General And Family Physician,
Above answer was peer-reviewed by : Dr. Kampana
doctor
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Follow up: Dr. Zubayer Alam (15 hours later)
Very good answer and thank you. I have had 2 endoscopies in the last 15 years. last one nine years ago with no findings. Is an irregular z-line always found to be barretts esoph.? Is an irregular z-line always considered less than 1 cm? And larger would be called something else? Finally , how many cases of an irregular z-line are inflamation rather than barretts EsopH? Thank you in advance for your informed advice.
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Follow up: Dr. Zubayer Alam (0 minute later)
Very good answer and thank you. I have had 2 endoscopies in the last 15 years. last one nine years ago with no findings. Is an irregular z-line always found to be barretts esoph.? Is an irregular z-line always considered less than 1 cm? And larger would be called something else? Finally , how many cases of an irregular z-line are inflamation rather than barretts EsopH? Thank you in advance for your informed advice.
doctor
Answered by Dr. Zubayer Alam (1 hour later)
Brief Answer:
Please see the detailed answer below.

Detailed Answer:
Hi,

Thank you so much for joining again. Usually an irregular z line is found in case of Barrett's oesophagus. But finding irregular z line undergoing endoscopy doesn't confirm Barrett's oesophagus. But, it may be found most of cases of Barrett's oesophagus. Barrett's esophagus is confirmed by biopsies. And biopsy will show intestinal metaplasia that is the confirmation of Barrett's oesophagus.

An rregular z line should be <1 cm according to its definition. Larger than that may be called long segment.

In some cases, irregular z line may be found without having Barrett's oesophagus. Those z lines are normal variant. Usually 10-15 % of population may have z lines without having Barrett's oesophagus undergoing routine endoscopy. As you had no irregular z line on your first endoscopy report, so your irregular z line has been developed by injuries due to chronic severe acid reflux. For that reason, your irregular z line is linked to Barrett's oesophagus.

Take care. Hope I have answered your questions. Let me know if I can assist you further.

Regards,
Dr. Zubayer Alam, General And Family Physician,
Above answer was peer-reviewed by : Dr. Prasad
doctor
doctor
Answered by Dr. Zubayer Alam (0 minute later)
Brief Answer:
Please see the detailed answer below.

Detailed Answer:
Hi,

Thank you so much for joining again. Usually an irregular z line is found in case of Barrett's oesophagus. But finding irregular z line undergoing endoscopy doesn't confirm Barrett's oesophagus. But, it may be found most of cases of Barrett's oesophagus. Barrett's esophagus is confirmed by biopsies. And biopsy will show intestinal metaplasia that is the confirmation of Barrett's oesophagus.

An rregular z line should be <1 cm according to its definition. Larger than that may be called long segment.

In some cases, irregular z line may be found without having Barrett's oesophagus. Those z lines are normal variant. Usually 10-15 % of population may have z lines without having Barrett's oesophagus undergoing routine endoscopy. As you had no irregular z line on your first endoscopy report, so your irregular z line has been developed by injuries due to chronic severe acid reflux. For that reason, your irregular z line is linked to Barrett's oesophagus.

Take care. Hope I have answered your questions. Let me know if I can assist you further.

Regards,
Dr. Zubayer Alam, General And Family Physician,
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Above answer was peer-reviewed by : Dr. Prasad
doctor
Answered by
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Dr. Zubayer Alam

General & Family Physician

Practicing since :2008

Answered : 1286 Questions

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Hi I Had An Upper Endoscopy Yesterday. . I Have

Hi I had an upper endoscopy yesterday. . I have Gerd or reflux and my last one was 11 years ago along with colonoscopy and was perfectly normal. 11 years ago I went on the XXXXXXX diet and for the first time in my life I had reflux that sent me to the emergency room. I took acifex for a couple of years. That quit working and I went on dexilant 60mg. Took that for a couple of years and was able to get off that for around 6 years or more. During the stress and the pandemic ireflux started up again. I am on it now. My Question. I had a routine endoscopy and colonoscopy. I had 4 small polyps that my Dr. said were no big worry. She took biopsies of my esophhogus etc and thew only finding was chronic gastritis and z-line irregular at thr gastroesophageal juncion. Biopsied, Normal duodenum. I am now freaking out as to what all this means. Could you please explain. I know the biopsy will answer everything but that could be 10 days to 2 weeks.