
Hi There, I Was Wondering If Taking 20 Mg Of

Question: Hi there,
I was wondering if taking 20 mg of Amitriptyline will interfere with levothyroxine absorbtion?
These meds are taken at 8pm for Amitriptyline and 6am for levothyroxine.
I have no thyroid.
Since starting Amitriptyline, my tsh has dropped from . 1 to . 376. I need to be around . 1 for optimal health.
I've read on healthline that levothyroxine absorbtion was inhibited by amitriptyline.
I'm normally very in tune to my levels and it should never have dropped like this. I can't figure out anything else.
I was wondering if taking 20 mg of Amitriptyline will interfere with levothyroxine absorbtion?
These meds are taken at 8pm for Amitriptyline and 6am for levothyroxine.
I have no thyroid.
Since starting Amitriptyline, my tsh has dropped from . 1 to . 376. I need to be around . 1 for optimal health.
I've read on healthline that levothyroxine absorbtion was inhibited by amitriptyline.
I'm normally very in tune to my levels and it should never have dropped like this. I can't figure out anything else.
Brief Answer:
Amytriptiline can interfere with levothyroxine absorption.
Detailed Answer:
Hello dear and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.
Amytriptiline can interfere the absorption of Levothyroxine.
I recommend changing the timing of the medications.
The absorption of levothyroxine occurs within 3 hours of ingestion.
So, you can try to take Amytriptiline in the evening. It will also help with your sleep.
Hope I have answered your query. Let me know if I can assist you further.
Kind regards!
Dr.Dorina Gurabardhi
General &Family Physician
Amytriptiline can interfere with levothyroxine absorption.
Detailed Answer:
Hello dear and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.
Amytriptiline can interfere the absorption of Levothyroxine.
I recommend changing the timing of the medications.
The absorption of levothyroxine occurs within 3 hours of ingestion.
So, you can try to take Amytriptiline in the evening. It will also help with your sleep.
Hope I have answered your query. Let me know if I can assist you further.
Kind regards!
Dr.Dorina Gurabardhi
General &Family Physician
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Above answer was peer-reviewed by :
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