Question: History of anxiety. I have been under a psychiatrist's care but have realized a lot of my problems have been due to excess acetylcholine. SSRI'S are anticholinergic so they helped me to great extent but not completely. However SSRI'S only target the muscarnic receptors and not the nicotine receptors. I realized that nicotine, acetylcholine and ethanol can all activate the nicotinic receptors in the adrenal medulla and the potential action is secretion of adrenaline. So I do have high adrenaline as well in urine test



In fact a drug that was used for hypertension was actually a nicotine antagonist. So there is a connection between acetylcholine (nicotinic receptors) and adrenaline.







Anytime I eat foods high in choline like egg, meat etc.. I feel overstimulated and terrible.



I tested my pseudo cholinesterase enzyme and it shows the enzyme being overloaded. I test it again after eating foods high in choline and the cholinesterase enzyme value shoots up..







I have PON1 (Paroxanase) Mutations and eating nightshades makes me feel horrible. I am now certain that excess acetylcholine is the root cause of a my problems.











How do we solve this? Any ideas