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How Can I Handle Anxiety And Restlessness While Taking Valsartan And Chlorthalidone?

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Posted on Fri, 22 Sep 2023
Question: currently taking Valsartan 320 for high b/p. My PCP just added Chlorthalidone 25. I could not tolerate 25 mg so am halving the pills. I do not do well with diuretics however it’s the most effective foe my b/p. Th new pill makes me jittery and anxious. In your opinion would stopping the Valsartan help since it was no longer effective anyway.
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Answered by Dr. Ilir Sharka (1 hour later)
Brief Answer:
I would explain as follows:

Detailed Answer:

Hello,

I passed carefully through your question and would explain that your symptoms seem to be related to Chlorthalidone adverse effects.

You should know that anxiety and restlessness is a common adverse effect of this drug.

For this reason, I would recommend taking half of the dose (like you have already done) or even stop taking it.

Regarding Valsartan, it seems to be not very effective in controlling high blood pressure.

For this reason, I would recommend making some changes to your current therapy :

a) -Switching from valsartan to another ARB (Telmisartan, Olmesartan) or an ACEI (Ramipril, Berlipril, etc.).
b) -Adding new drugs to your current therapy. In this regard, I would recommend adding a calcium channel blocker (Amlodipine, Lercanidipine, etc.) or Moxonidine.

You should discuss with your doctor about the above treatment options.

Hope you will find this answer helpful!

Wishing you all the best, feel free to ask further..

Dr. Iliri

Note: For further queries related to coronary artery disease and prevention, click here.

Above answer was peer-reviewed by : Dr. Arnab Banerjee
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Answered by
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Dr. Ilir Sharka

Cardiologist

Practicing since :2001

Answered : 9545 Questions

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How Can I Handle Anxiety And Restlessness While Taking Valsartan And Chlorthalidone?

Brief Answer: I would explain as follows: Detailed Answer: Hello, I passed carefully through your question and would explain that your symptoms seem to be related to Chlorthalidone adverse effects. You should know that anxiety and restlessness is a common adverse effect of this drug. For this reason, I would recommend taking half of the dose (like you have already done) or even stop taking it. Regarding Valsartan, it seems to be not very effective in controlling high blood pressure. For this reason, I would recommend making some changes to your current therapy : a) -Switching from valsartan to another ARB (Telmisartan, Olmesartan) or an ACEI (Ramipril, Berlipril, etc.). b) -Adding new drugs to your current therapy. In this regard, I would recommend adding a calcium channel blocker (Amlodipine, Lercanidipine, etc.) or Moxonidine. You should discuss with your doctor about the above treatment options. Hope you will find this answer helpful! Wishing you all the best, feel free to ask further.. Dr. Iliri