How Can Delayed Menstruation Despite Taking Duphaston Be Treated?

Posted on Fri, 22 Sep 2017

Question: Hi, i am 18 years old and didn't have my period since 18 months. My Gynecologist diagnosed me with PCOS and put me on Duphaston (2 tablets/day for 10 days). But now it's been 15 days since I stopped Duphsaton and still did not have my period. I'm sure that I am not pregnant. Would you please tell me why and what should I do ?

Answered by Dr. Deepti Verma (26 minutes later)

Brief Answer:
Uterine lining likely to be less

Detailed Answer:
Hi dear,
I have gone through your question and understand the concerns.
Sometimes, duphastone do not induces periods of the uterine lining is not well developed due to the hormonal disturbance.
If the uterine lining is less, then you will be needing both estrogen and progesterone tablets to Induce the periods..I will suggest you to get an ultrasound done to confirm the uterine lining and get further treatment accordingly.
Hope you found the answer helpful.
Regards
Dr Deepti Verma
OBGYN

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Deepti Verma (14 minutes later)

In this case, do you recommend birth control pills ? or HRT like cyclo-progenova ?

Answered by Dr. Deepti Verma (9 hours later)

Brief Answer:
Estrogen and progesterone

Detailed Answer:
Hi dear,
In this situation, Only estrogen ( Progynova)needs to be given for initial 14 days, followed by both estrogen and progesterone( Progynova and Deviry) for next 7 days.
This will induce the periods.
Regards
Dr Deepti Verma

Above answer was peer-reviewed by : Dr. Kampana

Follow up: Dr. Deepti Verma (1 hour later)

Hi Dr XXXXXXX

Thank you for your answers. I Have one more question:

Is there any health risks taking Hormone replacement? and what are the possible side effects?

Answered by Dr. Deepti Verma (10 hours later)

Brief Answer:
Various side effects

Detailed Answer:
Hi dear,

The hormonal replacement can lead to weight gain, mood changes, water retention, gastritis.

There are no major health related risks if taken for 3-6 months, which is the recommended treatment in PCOS.

Regards
Dr Deepti Verma

Above answer was peer-reviewed by : Dr. Arnab Banerjee

Follow up: Dr. Deepti Verma (20 hours later)

Hi Dr,
Still have on more question:

What if I don't take Hormone replacement, is there any risks on my health?

Answered by Dr. Deepti Verma (3 hours later)

Brief Answer:
No adverse effect

Detailed Answer:
Hi dear,

There is no risk to your health if you do not take a hormonal replacement.
You should have your periods at least every 3-4 months.

Regards
Dr Deepti Verma

Above answer was peer-reviewed by : Dr. Arnab Banerjee