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How Long Does It Take For Zoloft To Have And Effect?

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Posted on Tue, 24 Feb 2015
Question: How long does it take for Zoloft to show improvement in depression?
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Answered by Dr. Dr. Rovena (2 hours later)
Brief Answer:
it may take few weeks.

Detailed Answer:
Hello!

Welcome to Healthcare Magic.

The necessary time for a medication to give effect is related with it's mecanism of action.
Zoloft (Sertraline ) acts by inreasing the level of Serotonine in brain.Since this is a complex process involving neurotransmitters and the bild up of receptors in brain ,it takes some time before clinical improvement can be noticed.
It may take a few weeks until you feel improvement of depression symptoms.
This time is different in every person but it can vary from 2-4 weeks.Just be patient and give it some time to work.The improvements will be gradual but stable.

Hope this is helpful to you.
Let me know if you have any other question or doubt to clarify.I will be happy to assist you further.

Kind regards,
Dr.Rovena Murati
Note: For further guidance on mental health, Click here.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Dr. Rovena

General & Family Physician

Practicing since :2013

Answered : 1243 Questions

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How Long Does It Take For Zoloft To Have And Effect?

Brief Answer: it may take few weeks. Detailed Answer: Hello! Welcome to Healthcare Magic. The necessary time for a medication to give effect is related with it's mecanism of action. Zoloft (Sertraline ) acts by inreasing the level of Serotonine in brain.Since this is a complex process involving neurotransmitters and the bild up of receptors in brain ,it takes some time before clinical improvement can be noticed. It may take a few weeks until you feel improvement of depression symptoms. This time is different in every person but it can vary from 2-4 weeks.Just be patient and give it some time to work.The improvements will be gradual but stable. Hope this is helpful to you. Let me know if you have any other question or doubt to clarify.I will be happy to assist you further. Kind regards, Dr.Rovena Murati