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How Serious Are The Recent ALC/Lymphocytes Counts Below In The

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Posted on Fri, 11 Dec 2020
Question: How serious are the recent ALC/Lymphocytes counts below in the context of the current condition of a male in his early 70's? Could they be transient?

11/20 WBC 4.5 Thousand/uL; RBC 4.70 Million/uL; Neutrophils, absolute 3,560 cells/uL; Neutrophils 79.1%; Lymphocytes, absolute 477 cells/uL; Lymphocytes 10.6%. (Other CBC Differential counts in range; last test in 5/19 in range.)

Other CBC and CMP values in range. Lipid tests, PSA, and Testosterone in range.

Current condition: Stage 2 Kidney failure. Widespread Rheumatoid arthritis developed over last 12 months with ~ 5% body weight loss during that period; severe 1/20-7/20; improvement; moderate relapse 9/20-10/20: Prednisone 5 mg + Hydroxychloroquine bid 200 mg since May. Primary Hyperparathyroidism (test values out of range). Recent Urological infection: Doxycyxline 200 mg about 30 days (decades-long common problem). Gout. Hypertension. No COVID-19 indications.
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Answered by Dr. Dr.Dorina Gurabardhi (1 hour later)
Brief Answer:
Low lymphocyte levels are related to autoimmune diseases.

Detailed Answer:
Hello dear and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice.

Low lymphocytes can be related to many medical conditions.
In this presentation they can be related to two causes:
-The use of prednisone
-The presence of rheumatoid arthritis, which is an autoimmune disease.
In this case the changes in the blood count are completely normal.
The values of the lymphocytes are usually transient.
They are related to the condition of the autoimmune disease.


Hope I have answered your query. Let me know if I can assist you further.

Kind regards!

Dr.Dorina Gurabardhi
General &Family Physician
Note: For further follow up on related General & Family Physician Click here.

Above answer was peer-reviewed by : Dr. Raju A.T
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Answered by
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Dr. Dr.Dorina Gurabardhi

General & Family Physician

Practicing since :2013

Answered : 13558 Questions

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How Serious Are The Recent ALC/Lymphocytes Counts Below In The

Brief Answer: Low lymphocyte levels are related to autoimmune diseases. Detailed Answer: Hello dear and Welcome to ‘Ask A Doctor’ service. I have reviewed your query and here is my advice. Low lymphocytes can be related to many medical conditions. In this presentation they can be related to two causes: -The use of prednisone -The presence of rheumatoid arthritis, which is an autoimmune disease. In this case the changes in the blood count are completely normal. The values of the lymphocytes are usually transient. They are related to the condition of the autoimmune disease. Hope I have answered your query. Let me know if I can assist you further. Kind regards! Dr.Dorina Gurabardhi General &Family Physician