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How To Diagnose Cushing's Disease?
Question: How to diagnose Cushing Disease
Brief Answer:
combination of suspicion and tests
Detailed Answer:
Good day
Noted your concern. Cushings disease is due to excess production of steroids by body or by excess intake of steroid containing medicines. A high index of suspicion is required to diagnose minor degree of cushings where as severe form of disease is very obvious by characteristic body appearance.
Usually there will be weight gain, muscle weakness, purplish stretch marks in abdomen, moon like shape of face, increase in pimples etc.Some may have visual problems.
Once suspected , it is diagnosed by a series of tests. There are 3 types of tests. 1) screening tests b) confirmation tests c) Scans
Screening tests are either 24 hour urine free cortisol estimation , midnight salivary cortisol, overnight dexamethasone suppression tests.
We do screenings tests twice. Later a Confirmation test is done.
Regards
Binu
combination of suspicion and tests
Detailed Answer:
Good day
Noted your concern. Cushings disease is due to excess production of steroids by body or by excess intake of steroid containing medicines. A high index of suspicion is required to diagnose minor degree of cushings where as severe form of disease is very obvious by characteristic body appearance.
Usually there will be weight gain, muscle weakness, purplish stretch marks in abdomen, moon like shape of face, increase in pimples etc.Some may have visual problems.
Once suspected , it is diagnosed by a series of tests. There are 3 types of tests. 1) screening tests b) confirmation tests c) Scans
Screening tests are either 24 hour urine free cortisol estimation , midnight salivary cortisol, overnight dexamethasone suppression tests.
We do screenings tests twice. Later a Confirmation test is done.
Regards
Binu
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
How do you differentiate Cushings from Addisons Disease, and Syndrome of inappropriate ADH?
Brief Answer:
They are different
Detailed Answer:
Cushings disease is steroid excess. XXXXXXX is steroid deficiency. In XXXXXXX usually the patient is too tired and lose weight. The skin may turn darker as well.
In Syndrome of Inappropriate ADH secretion (SIADH ), patient develop low sodium levels, confusion and lethargy. XXXXXXX cam mimick like SIADH. We need to rule out XXXXXXX while dealing with a case of SIADH.
They are different
Detailed Answer:
Cushings disease is steroid excess. XXXXXXX is steroid deficiency. In XXXXXXX usually the patient is too tired and lose weight. The skin may turn darker as well.
In Syndrome of Inappropriate ADH secretion (SIADH ), patient develop low sodium levels, confusion and lethargy. XXXXXXX cam mimick like SIADH. We need to rule out XXXXXXX while dealing with a case of SIADH.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
What is the best treatment for Cushing Disease?
Brief Answer:
surgery is the preferred treatment
Detailed Answer:
Treatment is based on the cause. In Cushings syndrome we try to find out where the lesion is.
When the lesion is localised, the best treatment is surgery. When surgery is not possible, or when lesion can not be localised, then certain drugs can be used.
surgery is the preferred treatment
Detailed Answer:
Treatment is based on the cause. In Cushings syndrome we try to find out where the lesion is.
When the lesion is localised, the best treatment is surgery. When surgery is not possible, or when lesion can not be localised, then certain drugs can be used.
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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