I Have 448000 Platelets Count And A Few Giant Platelets

Posted on Sat, 13 Jul 2019

Question: I have 448000 platelets count and a few giant platelets seen. A mild thrombocytosis. Is this normal?
What happens?

Answered by Dr. Shailja Puri (1 hour later)

Brief Answer:
The platelet count is within normal range

Detailed Answer:
Hello,
Thanks for posting your query on HealthcareMagic.
Normal platelet count ranges between 1,50,000 to 4,50,000.
Thus, your platelet count is within normal biological range.
Platelet count can increase as a result of infection or inflammation.
The counts return back to normal once the infection and inflammation are treated.
Do you platelets remain in this range only or this is the first time that you have got platelet count on higher side of the range?
Presence of giant platelets are seen in conditions wherein immature platelets are released in peripheral blood.
Kindly, post your comments for further discussion.

Thanks and take care
Dr Shailja Puri
KINDLY HIT THANKS

Above answer was peer-reviewed by : Dr. Yogesh D

Follow up: Dr. Shailja Puri (1 hour later)

I understand that the count is within the range but (due to the presence of giant platelets, the count could be higher than the reading by automated platelet count) was mentioned on the report. Kindly can you help me understand the cause of increased platelets count along with few giant platelets seen.
I have taken a blood test previously on 04/05/2018 where my platelets count was 4.03 lakhs/cumm the range being (1.5-4.1).
But no gaint platelets at that time.

Answered by Dr. Shailja Puri (4 hours later)

Brief Answer:
The platelet count is normal on previous occasion

Detailed Answer:
Hello and welcome again,
The platelet counts are normal on previous occasional.
By definition, giant platelets are platelets having equal to that of red blood cells (RBCs).
There are very rare conditions associated with giat platelets and these conditions are usually associated with low platelet count.
In my experience the giant platelets mentioned often in reports are actually macro-platelets and not giant platelets. Macro-platelets are platelets which are slightly larger in size as compared to normal platelets.
Macro-platelets can be seen in viral infections. Macro-platelets do not indicate any disease process, infact they are indicative of regeneration of platelets in bone marrow.
You may follow up platelet count on regular basis.

Thanks and take care
Dr Shailja Puri
KINDLY HIT THANKS

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Shailja Puri (12 hours later)

So if I went to a specialist what will be the further diagnosis method or treatment? A mild thrombocytosis is nothing to be worried righ?

Answered by Dr. Shailja Puri (7 hours later)

Brief Answer:
Currently there is nothing to worry

Detailed Answer:
Hello and welcome again,
Currently there is nothing to worry.
However, you can follow the platelet counts with regular platelet count check.
If the platelet count remains in this range, there is nothing to worry.
Any sudden increase in platelet count e.g. beyond 7-8 lakhs needs without any obvious cause will require specialist attention.

Thanks and take care
Dr Shailja Puri

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Above answer was peer-reviewed by : Dr. Vaishalee Punj