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I Have Iron Deficiency Anemia Rbc 4.7 Hgb 10.4 Mcv

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Posted on Sun, 21 Jul 2019
Question: I have iron deficiency anemia
rbc 4.7 hgb 10.4 mcv forgot but clearly microcytic ferritin 1.7

had nissen 1.5 years ago have dumping syndrome...recent egd colonoscopy revealed moderate gastritis and esophagitis with grade b

? could dumping syndrome cause iron deficiency rapid transport of nutrients across duodenum and small bowel leading to malabsorption? Also take 40 mg omeperazole recent studies show this may alone lead to iron deficiency.
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Follow up: Dr. Ramesh Kumar (0 minute later)
I have iron deficiency anemia
rbc 4.7 hgb 10.4 mcv forgot but clearly microcytic ferritin 1.7

had nissen 1.5 years ago have dumping syndrome...recent egd colonoscopy revealed moderate gastritis and esophagitis with grade b

? could dumping syndrome cause iron deficiency rapid transport of nutrients across duodenum and small bowel leading to malabsorption? Also take 40 mg omeperazole recent studies show this may alone lead to iron deficiency.
default
Follow up: Dr. Ramesh Kumar (3 minutes later)
could moderate gastritis esophagitis lead to microscopic loss of blood that could lead to deficiency of iron?
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Follow up: Dr. Ramesh Kumar (0 minute later)
could moderate gastritis esophagitis lead to microscopic loss of blood that could lead to deficiency of iron?
doctor
Answered by Dr. Ramesh Kumar (6 hours later)
Brief Answer:
Compromised acid secretion is responsible for it.

Detailed Answer:
Hello and thanks for choosing 'Ask a Doctor' service for your query.
I've gone through your query in details.

See During fundoplication surgery, the upper curve of the stomach (the fundus) is wrapped around the esophagus and sewn into place so that the lower portion of the esophagus passes through a small tunnel of stomach muscle. These parts of the stomach secrete acid which converts the ferric form of iron present in food into ferrous form(which body can absorb).

Now as a large part of the stomach is used in surgery there is mild to moderate deficiency of acid secreted by oxyntic cells of the stomach, therefore, the iron is taken (ferric form) is not converted to ferrous form(absorbable).

On top of that, dumping syndrome causes food to move rapidly across the small intestines. This is the part where cynacobalamine is absorbed. They act as nets which trap iron hence giving Red blood cells normal size and shape(Normocytic).

Esophagitis and gastritis, unless is associated with erosion and loss of blood, has no role in this. To be sure get a stool for occult blood test done. If there is leakage of blood from any part of gut it would be reflected in this test.

Omeprazole 40 mg would take decades to do this It's among the safest medicines available in modern medicine(Don't read unnecessary articles on net written to get views.If you want to read prefer articles at NCBI site only).

Suggestions:
Take Iron polypeptide tablets 12 mg once daily for 1 month followed by 6mg once for 3 months.

A minimum of 3 months would be taken to replete your depleted iron stores. This is a new salt and won't cause any problem like constipation or diarrhea.
Take Vitamin B 12 capsule once daily.

Follow up after a month. Get a Complete blood count done.

Hope I was easy to understand and helpful.
Follow-ups are welcome.
Thank you


Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
doctor
Answered by Dr. Ramesh Kumar (0 minute later)
Brief Answer:
Compromised acid secretion is responsible for it.

Detailed Answer:
Hello and thanks for choosing 'Ask a Doctor' service for your query.
I've gone through your query in details.

See During fundoplication surgery, the upper curve of the stomach (the fundus) is wrapped around the esophagus and sewn into place so that the lower portion of the esophagus passes through a small tunnel of stomach muscle. These parts of the stomach secrete acid which converts the ferric form of iron present in food into ferrous form(which body can absorb).

Now as a large part of the stomach is used in surgery there is mild to moderate deficiency of acid secreted by oxyntic cells of the stomach, therefore, the iron is taken (ferric form) is not converted to ferrous form(absorbable).

On top of that, dumping syndrome causes food to move rapidly across the small intestines. This is the part where cynacobalamine is absorbed. They act as nets which trap iron hence giving Red blood cells normal size and shape(Normocytic).

Esophagitis and gastritis, unless is associated with erosion and loss of blood, has no role in this. To be sure get a stool for occult blood test done. If there is leakage of blood from any part of gut it would be reflected in this test.

Omeprazole 40 mg would take decades to do this It's among the safest medicines available in modern medicine(Don't read unnecessary articles on net written to get views.If you want to read prefer articles at NCBI site only).

Suggestions:
Take Iron polypeptide tablets 12 mg once daily for 1 month followed by 6mg once for 3 months.

A minimum of 3 months would be taken to replete your depleted iron stores. This is a new salt and won't cause any problem like constipation or diarrhea.
Take Vitamin B 12 capsule once daily.

Follow up after a month. Get a Complete blood count done.

Hope I was easy to understand and helpful.
Follow-ups are welcome.
Thank you


Above answer was peer-reviewed by : Dr. Arnab Banerjee
doctor
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Follow up: Dr. Ramesh Kumar (2 hours later)
If i now have fewer parietal cells secreting acid it seems logical that omeperazole would exacerbate the ph problem creating even higher ph thus decreasing iron absorption ?
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Follow up: Dr. Ramesh Kumar (0 minute later)
If i now have fewer parietal cells secreting acid it seems logical that omeperazole would exacerbate the ph problem creating even higher ph thus decreasing iron absorption ?
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Follow up: Dr. Ramesh Kumar (2 minutes later)
oh forgot will iron cause a positive occult blood test?
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Follow up: Dr. Ramesh Kumar (0 minute later)
oh forgot will iron cause a positive occult blood test?
doctor
Answered by Dr. Ramesh Kumar (1 hour later)
Brief Answer:
Your explaination is absolutely correct but we can't neglect gastritis also

Detailed Answer:
Hi,
1)Definitely yes.
But every problem has major and minor factors.Just taking Omeprazole after fundoplication can't make you anemic though it can have a additive effect.
Option you have.
You may switch over to H 2 blockers-Ranitidine (They don't effect the baseline secretion of acid but just supress excess acid secretion but problem is control of gastritis and esophagitis is not as good as compared to proton pump inhibitors.)
So considering your erosive gastritis and esophagitis we can take calculated risk of using omeprazole and can give you iron polypeptide tablet whose absorption is independent of pH.They are the latest catagory of salt and are highly effective.

Withdrwaing Omeprazole or PPIs may give you rebound acid reflux and gastritis related nausea,So we can't just take you off it.

2)Heme part of hemoglobin contains heme(iron) and globin.
If there are mild bleeding points inside the blood these unbroken heme would be detected by the test.

So to sum up you have two options-
1)Switch over to Rantitidine 150 mg once or twice daily and see if it helps you.
2)Easy one start taking Iron polypeptide 12mg once.Absorption being independent of pH no need to worry.
These are just suggestions.
However in medical science primary rule is to examine your patient before suggesting anything.
unfortunately that can't be done online.
So you may take a print out of these answers and discuss it with your primary Gastroenterologist and see what he/she says and follow up with his answer.In case of appointment problems you can mail these explaination and take his views too.

Hope you understand what I tried to explain to you.
Follow ups are welcome.
Thank you.
If you are satisfied with answer do rate it otherwise please suggest how to make answers better.
Feel free to follow up.
Warm regards.
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
doctor
Answered by Dr. Ramesh Kumar (0 minute later)
Brief Answer:
Your explaination is absolutely correct but we can't neglect gastritis also

Detailed Answer:
Hi,
1)Definitely yes.
But every problem has major and minor factors.Just taking Omeprazole after fundoplication can't make you anemic though it can have a additive effect.
Option you have.
You may switch over to H 2 blockers-Ranitidine (They don't effect the baseline secretion of acid but just supress excess acid secretion but problem is control of gastritis and esophagitis is not as good as compared to proton pump inhibitors.)
So considering your erosive gastritis and esophagitis we can take calculated risk of using omeprazole and can give you iron polypeptide tablet whose absorption is independent of pH.They are the latest catagory of salt and are highly effective.

Withdrwaing Omeprazole or PPIs may give you rebound acid reflux and gastritis related nausea,So we can't just take you off it.

2)Heme part of hemoglobin contains heme(iron) and globin.
If there are mild bleeding points inside the blood these unbroken heme would be detected by the test.

So to sum up you have two options-
1)Switch over to Rantitidine 150 mg once or twice daily and see if it helps you.
2)Easy one start taking Iron polypeptide 12mg once.Absorption being independent of pH no need to worry.
These are just suggestions.
However in medical science primary rule is to examine your patient before suggesting anything.
unfortunately that can't be done online.
So you may take a print out of these answers and discuss it with your primary Gastroenterologist and see what he/she says and follow up with his answer.In case of appointment problems you can mail these explaination and take his views too.

Hope you understand what I tried to explain to you.
Follow ups are welcome.
Thank you.
If you are satisfied with answer do rate it otherwise please suggest how to make answers better.
Feel free to follow up.
Warm regards.
Note: For further follow up on digestive issues share your reports here and Click here.

Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
Answered by
Dr.
Dr. Ramesh Kumar

Gastroenterologist

Practicing since :1986

Answered : 2910 Questions

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I Have Iron Deficiency Anemia Rbc 4.7 Hgb 10.4 Mcv

I have iron deficiency anemia rbc 4.7 hgb 10.4 mcv forgot but clearly microcytic ferritin 1.7 had nissen 1.5 years ago have dumping syndrome...recent egd colonoscopy revealed moderate gastritis and esophagitis with grade b ? could dumping syndrome cause iron deficiency rapid transport of nutrients across duodenum and small bowel leading to malabsorption? Also take 40 mg omeperazole recent studies show this may alone lead to iron deficiency.