
I Think I Have Some Sort Of AMPO Deficiency (

Your weakness and difficulty breathing can be explained by Faslodex.
Detailed Answer:
Hello,
Welcome to Ask A Doctor service.
I have gone through your query carefully and noted the history of breast cancer and pancreatitis and the use of Faslodex for breast cancer.
Both your problems of weakness in the limb muscles and difficulty breathing are well known side-effects of the medicine Faslodex.
Since you are feeling better with D-Ribose, you may continue that without any problem.
You are 80 years old, and if you were to have have any of the AMPO (glycogen storage disorders), or McArdles or Pompe you would have not survived past your childhood or early adolescence.
Such disorders are diagnosed much earlier because they present with symptoms very early on in life, not at the age of 75 years as in your case, please stop thinking of such congenital or genetic causes for your weakness.
I hope that answers your query.
Wishing you good health.
Best wishes.


Maybe age related.
Detailed Answer:
Hello again,
Thank you very much for clarifying the issue. Apologies for the delay in getting back to you.
If the problem started before you started taking Faslodex then it is not due to Faslodex, it might have been made worse by Faslodex.
Morphine does not cause pancreatitis even when injected directly into a vein.
When we do use morphine for pain relief we inject it through all the available routes depending on the accessibility and severity of pain including into the veins and I have not come across pancreatitis being caused by morphine in my practice.
Pancreatitis is almost always is due to alcohol consumption.
Surgery for breast cancer is unlikely to cause fatigue, rather breast cancer itself could cause fatigue.
If you have been evaluated by 3 different neurologists and they cannot find any cause, then it could be chronic fatigue syndrome coupled with old age.
I can not be 100% sure without knowing your entire medical history and data.
I hope diabetes has been ruled out.
I my opinion your fatigue is unlikely to be due to any organic cause, it is more likely to be due to neurochemical imbalance.
Do discuss chronic fatigue syndrome with your neurologists and proceed further.
Continue D-Ribose if it is helping you.
I hope this information will be some help, please do write back to me if you have any more doubts or any specific queries.
Wishing you good health.
Best regards


I was told it is not Chronic Fatigue because it is only weak legs and breathing. I had the leg weakness before any body fatigue. I agree, the fatigue, at this point, is most likely from the Faslodex and cancer. However, the thing that is ruining my life is the inability to walk right. I can't give up because I have to tend to many projects like my orphanage in XXXXXXX I will keep hoping to find an answer. For now, I am thankful the Mito Cell is helping. All the Best to you.
Difficult to diagnose without examination and complete picture.
Detailed Answer:
Hello,
Thank you for providing the additional information.
As for the morphine incident, let me reassure you, morphine can be given by all routes, that is intravascular, intramuscular or by subcutaneous routes, so even if it extravasated out of the vein, it would not cause pancreatitis. Although there is animal experiment data suggesting that morphine can worsen already present pancreatitis and this has not been proven in humans though.
Alcohol is one of the causes of pancreatitis, but not the only cause, many drugs, including immunosuppressants and others can cause pancreatitis.
Weakness in specific parts of the body is most often due to a very tiny stroke in the brain affecting that specific part alone.
Or it is more likely to be due to some local cause.
Weakness can be fundamentally be divided into that caused due to a problem in the muscles or a problem with the nerves that supply those muscles.
Difficulty breathing can be due to many causes, muscles weakness is one of the last causes to be considered as there other potentially more serious conditions such as heart disease or lung disease to be ruled out first.
That said, I am not ruling out the possibility of muscle weakness in your case.
Chronic fatigue does usually affect the whole body, but may also affect muscles of breathing and thing muscles.
I am unable to come to any conclusion without being able to physically examine you in person and also look at what investigations have been done.
I am sorry to disappoint you like many of your previous doctors, but I am seriously limited in my ability without direct examination.
I wish you the very best and hope you find an answer sooner than later.
Warm regards


Thank you for understanding.
Detailed Answer:
Thank you very much for understanding.
I hope you get better soon.
Stay strong and be well.

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