Hi XXXXXXX
Dose of Neurofen, for two year old girl is two liquid doses of 25 mg separated by few hours. If fever/pain is not reduced after two doses, consult a doctor.
Giving the eight times the amount of that dose will is likely produce some side effects and it has the potential to produce serious effects:

Do not panic usually drugs which are available OTC have therapeutic index that is ratio of drug producing toxic effects to therapeutic dose around 10. Meaning thereby over ten times the advised therapeutic dose will be generally very XXXXXXX So by that calculation, you child has still not ingested a toxic dose.

Side Effects and toxic effects:
Ibuprofen is generally well-tolerated and most people do not experience any side effects. The most common side effects are related to stomach irritation and include abdominal pain, indigestion and nausea. These can mainly be avoided by taking the ibuprofen with food. Rarely, serious side effects such as ulceration or bleeding of the stomach or intestines may occur. These are more likely with high doses and in elderly people. If your child experiences any sign of bleeding from the stomach or bowels after taking this medicine, such as vomiting blood and/or passing black/tarry/bloodstained stools, you should consult your doctor immediately.
Very rarely, reactions (eg Stevens-Johnson syndrome, toxic epidermal necrolysis, exfoliative dermatitis). For this reason, you should consult your doctor if your child gets a skin rash or sores inside the mouth after taking this medicine.
Consult your doctor immediately if any of the following is there:
1.History of disorders affecting the stomach or intestines.
2.Kidney disease.
3.Liver disease.
4.Heart failure.
5.Children with blood clotting problems or taking anticoagulant medicines.
6. History of asthma.
7. History of allergies.
8. Diseases affecting connective tissue, eg systemic lupus erythematosus.
Not to be used in
10. Children under three months of age or weighing less than five kilograms.
11. Children taking other NSAIDs, including COX-2 inhibitors
12. This medicine should not be used if your child is allergic to one or any of its
ingredients. Please inform your doctor or pharmacist if your child has previously
experienced such an allergy.

If you feel your child has experienced an allergic reaction, inform your doctor or pharmacist immediately.

I hope my answer has been useful. If you have any followup question please get back I will be happy to answer the question.

With Best Wishes

Dr Anil Grover

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