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Is TPO Antibody Level Of 1,189 A Cause For Concern?
Question: What means a microsomal antibody (TPO) of 1,189. The lab told me that repeat the test two times, since is very high.
Brief Answer:
My advice is to repeat this test to another lab.
Detailed Answer:
Hi dear user
I have gone through your question.
I can understand your concern.
The determination of TPO antibody levels is the most sensitive test for detecting autoimmune thyroid disease (eg, Hashimoto thyroiditis, idiopathic myxedema, and Graves disease) and detectable concentrations of anti-TPO antibodies are observed in most patients with these disorders.
The frequency of detectable anti-TPO observed in nonimmune thyroid disease is similar to the 10% to 12% observed in a healthy population with normal thyroid function.
The highest TPO antibody levels are observed in patients suffering from Hashimoto thyroiditis. In this disease, the prevalence of TPO antibodies is about 90% of cases, confirming the autoimmune origin of the disease. These autoantibodies also frequently occur (60%–80%) in the course of Graves disease.
The reference ranges for anti-TPO is less than 35 IU/mL.
Your result is very high so my advice is to repeat this test to another lab but don't worry because this tes will help to diagnose your autoimune thyroid condition and is used from many clinical endocrinologists as a diagnostic tool in deciding whether to treat a patient with subclinical hypothyroidism.
Hope my information is useful for you.
Thank you for using HCM.
Wish you goog health.
My advice is to repeat this test to another lab.
Detailed Answer:
Hi dear user
I have gone through your question.
I can understand your concern.
The determination of TPO antibody levels is the most sensitive test for detecting autoimmune thyroid disease (eg, Hashimoto thyroiditis, idiopathic myxedema, and Graves disease) and detectable concentrations of anti-TPO antibodies are observed in most patients with these disorders.
The frequency of detectable anti-TPO observed in nonimmune thyroid disease is similar to the 10% to 12% observed in a healthy population with normal thyroid function.
The highest TPO antibody levels are observed in patients suffering from Hashimoto thyroiditis. In this disease, the prevalence of TPO antibodies is about 90% of cases, confirming the autoimmune origin of the disease. These autoantibodies also frequently occur (60%–80%) in the course of Graves disease.
The reference ranges for anti-TPO is less than 35 IU/mL.
Your result is very high so my advice is to repeat this test to another lab but don't worry because this tes will help to diagnose your autoimune thyroid condition and is used from many clinical endocrinologists as a diagnostic tool in deciding whether to treat a patient with subclinical hypothyroidism.
Hope my information is useful for you.
Thank you for using HCM.
Wish you goog health.
Above answer was peer-reviewed by :
Dr. Prasad
I send you the test , maybe you can see what is happening to me. I do not find appointments with a endo until december..:(. Here in my country they are very busy. :(.
Brief Answer:
I am happy to help you.
Detailed Answer:
Hi
With this first result of anti-TPO antibodies, the only think that we can deduct is that you have an autoimmune thyroid disease.
If you were my patient,i will order the thyroid tests to understand the actual thyroid function and perform a thyroid ultrasound to see the thyroid structure.
Maybe it will be necessary even a radioactive iodine uptake test (RAIU),optional .
Only after the information taken from this tests we can be able to reach the definitive diagnosis and to talk about the treatment(if this will be necessary).
If you can do this tests ,ask me a direct question and i will be happy to help.
Don't worry the high level of antimicrosomal antibodies doesn't mean any life-threatening condition.
Wish you very good health.
Dr.Elona
I am happy to help you.
Detailed Answer:
Hi
With this first result of anti-TPO antibodies, the only think that we can deduct is that you have an autoimmune thyroid disease.
If you were my patient,i will order the thyroid tests to understand the actual thyroid function and perform a thyroid ultrasound to see the thyroid structure.
Maybe it will be necessary even a radioactive iodine uptake test (RAIU),optional .
Only after the information taken from this tests we can be able to reach the definitive diagnosis and to talk about the treatment(if this will be necessary).
If you can do this tests ,ask me a direct question and i will be happy to help.
Don't worry the high level of antimicrosomal antibodies doesn't mean any life-threatening condition.
Wish you very good health.
Dr.Elona
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Above answer was peer-reviewed by :
Dr. REMY KOSHY
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