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Is A 3rd Generation HIV Antibody Test Result After 4.5 Months Of Exposure Conclusive?
Question: Is a 3rd Generation HIV Antibody test (Using Vitros ECi) after 4.5 months of possible exposure result negative is final and definite? Shall I need further test?
Brief Answer:
Yes , you may need another test
Detailed Answer:
Thanks for your question. This is Dr Matin, answering your query .
3rd Generation HIV Antibody test (Using Vitros ECi) are more sensitive for early infection than rapid antibody HIV tests and 2nd generation tests but less sensitive than 4th generation tests.
So I guess a 4th Generation test is warranted
Hope it helps.
Regards
Yes , you may need another test
Detailed Answer:
Thanks for your question. This is Dr Matin, answering your query .
3rd Generation HIV Antibody test (Using Vitros ECi) are more sensitive for early infection than rapid antibody HIV tests and 2nd generation tests but less sensitive than 4th generation tests.
So I guess a 4th Generation test is warranted
Hope it helps.
Regards
Above answer was peer-reviewed by :
Dr. Vinay Bhardwaj
What is the window period of 3rd generation antibody test?
Brief Answer:
21-24 Days
Detailed Answer:
Thanks for your response.
Window period is the length of time after infection /exposure that it takes for the virus to become detectable by HIV diagnostic tests. The length of the window period varies depending on the type of diagnostic test used and the method which is used to detect its antibody .
The window period varies slightly from person to person too. It is extremely rare for an HIV-infected person not to develop antibodies by 3 months after a potential exposure. When the person who tests negative for HIV antibodies 3 months after an exposure/infection does not require further testing unless he or she has had repeated exposures to HIV or if the antibody test results are incompatible with the person’s clinical history.
Third-generation tests detect all types of antibodies, which makes them more sensitive than the first-generation and second-generation tests. These assays can detect antibodies about 21-24 days after infection.So the window period here is 21-24 days, but the final time--3 months.This is universal too.
That is why we test a vulnerable /high risk patient -- three times -at base line, after 1 month and finally after 3 months.
Hope this helps.
http://bit.ly/askdrmatinahmedkhan
21-24 Days
Detailed Answer:
Thanks for your response.
Window period is the length of time after infection /exposure that it takes for the virus to become detectable by HIV diagnostic tests. The length of the window period varies depending on the type of diagnostic test used and the method which is used to detect its antibody .
The window period varies slightly from person to person too. It is extremely rare for an HIV-infected person not to develop antibodies by 3 months after a potential exposure. When the person who tests negative for HIV antibodies 3 months after an exposure/infection does not require further testing unless he or she has had repeated exposures to HIV or if the antibody test results are incompatible with the person’s clinical history.
Third-generation tests detect all types of antibodies, which makes them more sensitive than the first-generation and second-generation tests. These assays can detect antibodies about 21-24 days after infection.So the window period here is 21-24 days, but the final time--3 months.This is universal too.
That is why we test a vulnerable /high risk patient -- three times -at base line, after 1 month and finally after 3 months.
Hope this helps.
http://bit.ly/askdrmatinahmedkhan
Above answer was peer-reviewed by :
Dr. Shanthi.E
Doctor saab,
Thanks for the clarification. I did this test after 4 months 2 weeks of possible exposure. Can I consider it final?
I am quite healthy person. Since last 9 years never had fever sort of sickness. Just since last few months suffering from throat problem. ENT specialist classified it due to Post Nasal Drip.
Thanks for the clarification. I did this test after 4 months 2 weeks of possible exposure. Can I consider it final?
I am quite healthy person. Since last 9 years never had fever sort of sickness. Just since last few months suffering from throat problem. ENT specialist classified it due to Post Nasal Drip.
Brief Answer:
Yes, it is conclusive
Detailed Answer:
Thanks for your response.
Yes, it is conclusive once it is negative and exceeds the window period of 3 months.
Post nasal drip is a condition with Perennial /Seasonal Allergic Rhinits (in lay man term -bouts of sneezing, associated with nasal blockade and secretions coming in your throat once you cough--called 'post nasal drip'). The best part is you are getting it treated by an expert. So hang on over there and keep getting treated from ENT expert till he says it is essential for you.
Eosinophils are not judged by %, and this mistake is done by even general practitioners leave aside lay man.
We calculate the absolute value of eosinphils (suppose your total white blood cell count is 7000/mm3 and your eosinophil count is 5 %, means your total eosinophil count is 350/mm3.
We consider absolute eosinophil significant only when it is > 550 /mm3.
Guess I have explained everything and so I conclude over here
Keep well and remain healthy.
Regards
http://bit.ly/askdrmatinahmedkhan
Yes, it is conclusive
Detailed Answer:
Thanks for your response.
Yes, it is conclusive once it is negative and exceeds the window period of 3 months.
Post nasal drip is a condition with Perennial /Seasonal Allergic Rhinits (in lay man term -bouts of sneezing, associated with nasal blockade and secretions coming in your throat once you cough--called 'post nasal drip'). The best part is you are getting it treated by an expert. So hang on over there and keep getting treated from ENT expert till he says it is essential for you.
Eosinophils are not judged by %, and this mistake is done by even general practitioners leave aside lay man.
We calculate the absolute value of eosinphils (suppose your total white blood cell count is 7000/mm3 and your eosinophil count is 5 %, means your total eosinophil count is 350/mm3.
We consider absolute eosinophil significant only when it is > 550 /mm3.
Guess I have explained everything and so I conclude over here
Keep well and remain healthy.
Regards
http://bit.ly/askdrmatinahmedkhan
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Above answer was peer-reviewed by :
Dr. Ashwin Bhandari
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