Is A P 24 HIV 1 And 2 Test Conclusive At 70 Days Post Exposure?
on 68 or 69 day did western blot which came out negative ( this time no bands detected all negative ) , 70 days day did p24 hiv1 and hiv 2 negative !! today 74 day i did pcr rna waiting for result !! plez help
anxiety is killing me ..
Tenvir, potent ART abort if there was any infection. Nothing to worry
Detailed Answer:
Hi,
Welcome to HCM.
Thanks for posting your query.
First of all why you had numerous tests for HIV?
Your servant maid would not have HIV infection at all. Then where is the question of HIV for you? Your girl friend also tested negative for HIV combo test.
HIV 1 and 2 / P 24 Antigen test negative after 24, 33,42 and 70 days after high risk contact along with undetectable viral load with RNA PCR test on 24 days clearly ruled out HIV 1 infection (which is prevalent more than 99.5% everywhere in the world except in certain parts of Africa). Antibody part of the Combo test and western blot and immuno-Chromatography test become more conclusive after 12 weeks.
In your case as you are on steroids and Tenvir it may get delayed still more.
At the same time Tenvir 300 mg tablets taken by you, have effect to abort HIV 1 and 2 infection, if any, infection have occurred to you during that exposure as it has anti-retroviral effect both on HIV 1 and 2.
So there is no chance for you get HIV infection.
Dr S.Murugan
1)my question do i need to get my girlfriend tested again ? 2)cause if i had it she surely would have right ? 3) do i need to get tested again !
thx a lot for your advice !! i have lost sleep and 3 months now stopped working out and living .. i live in fear daily !!
GF unlikely to get infected. Rule out HIV 2 infection after 3 months
Detailed Answer:
Hi,
Welcome back.
1.As you are on Tenvir, if there was any infection, it would have been aborted as I had mentioned already. So there is no chance for your girl friend to acquired HIV infection from you.
2. All exposures are not necessarily infectious.There are 30-40% of the spouses of HIV positive people remain non-reactive in spite of their regular and prolonged sex contacts with their spouses and they are called as Sero- discordant couple. Likewise even if you have infection there are chances for her to remain uninfected in spite of your sex relationship.
3. Having undergone so many tests so far, it is better to rule out HIV 2 infection (less than 0.5% chance) by a rapid or ELISA test after 3 months and after 6 months as you are on steroid.
Dr S.Murugan
Welcome You are free from HIV 1 infection
Detailed Answer:
Hi XXXX,
You are almost HIV free. Be confident. Nothing to worry.
Dr S.Murugan
Your girl friend also free from HIV 1 Infection
Detailed Answer:
Hi,
Welcome back.
Definitely it is a good news. Your girl friend's tests also ruled out the HIV 1 infection in her.
Your test also will ensure that you are free from HIV infection
Dr S.Murugan
please let me know what does it say .
2) sir i want to rule out all SIT etc what test to do
3) after 90 days should i do p24 combo or some other test ?
Regards XXXXXXX
VDRL, HBSAg, HCV, Urine examination,HSV and Chlamydial test to rule out STI
Detailed Answer:
Hi,
Welcome back.
1.Your RNA PCR result reflects that it can not detect any HIV virus in your blood to its maximum possible extent.
2.Urine examination, Blood test for Syphilis, Hepatitis B and C, HSV 1 and 2 Ig G and M test are enough to rule out STI.
3. HIV 2 is yet to be ruled out. Combo test or any other antibody detecting test by 12 weeks would rule out HIV 2 also which may be a rarest and remote possibility.
Dr S.Murugan
You are free from HIV 1 INFECTION.
Detailed Answer:
Hi,
Welcome back.
HIV RNA PCR undetectable viral load after 74 days is definitely a good result.
Keep yourself relaxed.
Dr S.Murugan
screening for STD s is recommended
Detailed Answer:
Hi
Welcome back
Screening for all STDS is good. All tests are expected to come as negative. Good day to you
Dr S Murugan
Chlamydial PCR is preferable
Detailed Answer:
HI,
Welcome once again.
There are different serovars of Chlamydia causing a wide range of diseases like Trachoma (A,B,C), Lymphogranuloma (L1,L2,L3), inclusion conjuctivitis and Non gonococcal urethrits (D-K).
But usually we don't prefer to find the serovars separately. Only we prefer to fond whether Chlamydial infection is there or not.
PCR test for Chlamydia is preferable than with others.
Dr S.Murugan
Negative VDRL ensures that you are free from Syphilis
Detailed Answer:
Hi,
Welcome.
You are free from Syphilis.
Dr S.Murugan
Safe sex is always good.
Detailed Answer:
Hi XXXX,
you will get all negative results for the other test also. But here afterwards try to stick to safe sex to avoid unnecessary mental tension. Expecting to share your your good news in the coming days.
Dr S.Murugan
have attached my three reports ! kindly advice thx
HIV 1, SYPHILIS, HSV and HCV ruled out beyond any doubt.
Detailed Answer:
Hi,
Welcome back.
All results were in favor. You are free from Syphilis, HSV 1 and 2 infections, HIV 1 infection and HCV (as you had mentioned already). You had ruled out almost all major blood born diseases and STDs. These test reports after 74 days are conclusive.
Relax and be happy. Forget the past incidence. HIV 2 also will be likely to be non reactive.
Dr S.Murugan
HIV 2 can be ruled out by antibody test 90 days after the contact.
Detailed Answer:
Hi,
Welcome once again.
I will say 12 weeks is final to have the test. But better to have the test by 90 days after the contact, so that we need not have any doubt about the test report.
Dr S.Murugan
A good day ahead to you
Detailed Answer:
Hi,
Welcome and a good day to you!
ELISA. Rapid or 4th generation COMBO test preferred.
Detailed Answer:
Hi,
Welcome back.
HIV PCR test and P 24 Antigen test would not rule out HIV 2 infection.
4th generation COMBO test Ab 1/2 P 24 antigen test or any Rapid test, ELISA test can be done All are almost equally good and reliable. Western blot also can be done But it is less sensitive for HIV 2 is concern.
DR S.Murugan
i will be going for the test tommrow or dayafter ! also all the test i have done are form dr lal path lab and SRL , hope these are good labs and all test done were 4th gen combo or dual .so i will go for the same test sir from these labs ?
just a little nervous though sie and just praying !!
LAL PATH and SRL labs are highly reliable laboratories.
Detailed Answer:
Hi,
WELCOME once again.
Lal PATH LAB and SRL LABS are the best and reliable laboratories in XXXXXXX You can go with them confidently.
Dr S.Murugan
87 -88 days p 24 combo test hiv1 and hiv 2 anti body screening test (4th gen )is non reatice at lal path lab XXXXXXX ...have asked them to do weaternblot and pcr rna , report awaited for these two monday ! Plz advice further cource of action !
No further test is necessary. You are free from both HIV 1 and 2 infection.
Detailed Answer:
Hi,
Welcome back.
Negative HIV 4th generation test after 12 weeks (84 days) clearly ruled out both HIV 1 and 2. No more test is necessary for you. You do not need any further course of action and just forget about the incident and relax. Try to stick on safe sex in your future to avoid unnecessary mental tension.
Have good days ahead.
Dr S..Murugan
You are most welcome
Detailed Answer:
Hi XXXX,
I am happy to see you back with your normalcy. You are welcome. If you have no more questions to ask, you can close this conversation. You can meet me at SHIFA Hospitals, XXXXXXX Tamilnadu on all weekdays between 5-7.30 pm.
Dr S.Murugan
I will see you form sure at shifa !
Sir my questions ..
1) any specific condoms which offer good protection
2) can i resume normal life ( workout , running )
3) does my gf need testing ?
Thx sir !
you are free from HIV 1and2. Resume normal activities
Detailed Answer:
Hi,
Welcome back
RNA PCR undetectable and Combo tests non-reactive after 12 weeks confirm that youare free from both HIV 1and 2.
You can resume your normal sexual activities.
Your girlfriend not necessary to be tested
Dr S Murugan
Most welcome
Detailed Answer:
Hi,
You are welcome at any time.
Wish you have very good days ahead.
Dr S.Murugan