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Is An HIV Test Conducted At 22 Days Post Exposure Conclusive?

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Posted on Mon, 22 Sep 2014
Question: Dear doctor,

I have had the result of the HIV P24 Ag&Abs (HIV combo), tested on the 22day of exposure As per Dr. XXXXXXX advice. The result is non reactive as same as the result obtained after 12 days I had earlier.
What do you think?
doctor
Answered by Dr. Sankaranantham Murugan (1 hour later)
Brief Answer:
You are free from HIV 1 infection.

Detailed Answer:
Hi,
Welcome to HCM.
Thanks for posting your query.

HIV Combo test is the 4th generation test and highly reliable. It has two components (Combo).
Those are :
one is P24 antigen part . This will become conclusive by 3 weeks after the high risk activity. Whereas it usually includes only HIV 1 antigen which is the most common HIV infection (almost 100%).
The 2nd part of test is detecting the Antibodies against both HIV 1 and HIV 2. This will be detected only after the completion of window period (that is 8-12 weeks after exposure) as the antibodies start appearing only after 8-12 weeks.

So a negative Combo test at 22 days after the high risk exposure assures you that you free from HIV 1.
HIV 2 is yet to be ruled out after 12 weeks by repeating the test.
But the chances of HIV 2 infection is less than 1% only in the whole world other than in XXXXXXX
Dr S.Murugan
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Sankaranantham Murugan (12 hours later)
Dear Doctor,

Thank you for your reply.

Please advise which test should I have after 3 month to close this issue forever.

Also is there any comforting test can be done after 2 month?

Thank you
doctor
Answered by Dr. Sankaranantham Murugan (1 hour later)
Brief Answer:
Any antibody test after 12 weeks equally effective

Detailed Answer:
Hi,
Welcome back.

No comfortable test is necessary at 2 months. It would not comfort you in any way as it would not be conclusive.

Any rapid test, ELISA, EIA or a Combo test is equally good and reliable and conclusive by 12 weeks.
Just wait for few more days to get a more conclusive result. Your type of sexual act carries a negligible risk for HIV.
Dr S.Murugan
Note: Get personalized answers to your HIV related queries You can choose to talk face to face with your doctor. Book a Video Call now.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
Dr.
Dr. Sankaranantham Murugan

HIV AIDS Specialist

Practicing since :1974

Answered : 3110 Questions

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Is An HIV Test Conducted At 22 Days Post Exposure Conclusive?

Brief Answer: You are free from HIV 1 infection. Detailed Answer: Hi, Welcome to HCM. Thanks for posting your query. HIV Combo test is the 4th generation test and highly reliable. It has two components (Combo). Those are : one is P24 antigen part . This will become conclusive by 3 weeks after the high risk activity. Whereas it usually includes only HIV 1 antigen which is the most common HIV infection (almost 100%). The 2nd part of test is detecting the Antibodies against both HIV 1 and HIV 2. This will be detected only after the completion of window period (that is 8-12 weeks after exposure) as the antibodies start appearing only after 8-12 weeks. So a negative Combo test at 22 days after the high risk exposure assures you that you free from HIV 1. HIV 2 is yet to be ruled out after 12 weeks by repeating the test. But the chances of HIV 2 infection is less than 1% only in the whole world other than in XXXXXXX Dr S.Murugan