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Is Double Marker Test And Quad Test Necessary During Pregnancy?

Posted on Thu, 12 Jun 2014

Question: i m 18 weeks and 3 days pregnant today...
i had my nuchal scan at 12 weeks , genetic scan at 15 weeks and anomaly level 2 scan at 18 weeks and all are perfectly ok.
but somehow i did not get dauble marker or quad test
my question is :
is it important to get this test done or scan are enough to rule out anything wrong?
what test can i get at this stage?
also my age is 33 years and this is my first pregnancy

Answered by Dr. Sree Gouri SR (20 minutes later)

Brief Answer:
TIFFA scan

Detailed Answer:
Hi,
Thanks for the query.
Usually multi marker tests are advised when there is expected risk of chromosomal anomalies.
As all your previous investigations are normal, the risk is low in your case.
The only risk factor according to the history is age above 30 years.
If you want and if your doctor suggests you can go for quadruple test to rule out the possibility completely.
You can go for quadruple test at this gestational age.
And TIFFA(Targeted imaging for fetal anomalies) scan at around 20 weeks is advised.

Hope I have answered your query. I will be available to answer followup queries. If you are satisfied with the answer, please give your review at the end of discussion.
Take care.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Sree Gouri SR (8 hours later)

Till what week i can get quad test done?

actually initially i had fraternal twin pregnancy but one of the twins stopped growing at 9 weeks , so in my case is quad test result reliable?

Answered by Dr. Sree Gouri SR (16 hours later)

Brief Answer:
15 to 22 weeks

Detailed Answer:
Hi,
Quadruple test can be done between 15 to 22 weeks of gestation.
It will be more accurate between 16 to 18 weeks.
As you just crossed 18 weeks of gestation, you can go for quadruple test now.
Quadruple test measures the levels of pregnancy hormones in blood to estimate the risk of having chromosomal abnormality in the fetus.
Growth of the twins can get affected due to circulatory disturbances etc.
Usually if growth of one fetus gets stopped in early pregnancy, that will get vanished.
If your present ultrasound is showing one fetus only, quadruple test can give accurate result.

Take care.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Sree Gouri SR (9 hours later)

Thanks I got the quad test today n waiting for the results

I m 18 weeks 5 days today n still I haven't felt my baby kicks till now
Is it normal ?

Answered by Dr. Sree Gouri SR (14 hours later)

Brief Answer:
At around 20 weeks

Detailed Answer:
Hi,
Usually in first pregnancy the woman can perceive the fetal movements at around 20 weeks.
So, no need to worry.
Hopefully you will get quadruple test result as normal.
Take care.

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Sree Gouri SR (35 hours later)

I got the quad test and it is perfect

I went for a very loud movie today (Godzilla ) and also to a nightclub where the music was very loud and someone told me exposure to very loud music may harm the unborn baby? Or his ears
Is it true ??
I mean I hope very loud movie cannot cause miscarriage ?

Answered by Dr. Sree Gouri SR (7 hours later)

Brief Answer:
May not

Detailed Answer:
Hi,
Prolonged exposure to very loud sounds like industrial sounds can affect the hearing of the fetus.
But usually the music played in cinema halls or in night clubs will not be that much loud to harm the hearing of the fetus.
The amniotic fluid which is present around the baby can help in muffling the sounds.
And these type of sounds may not cause miscarriage also.
So, no need to worry.
But better to be careful in future.

Take care.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar