HealthCareMagic is now Ask A Doctor - 24x7 | https://www.askadoctor24x7.com

question-icon

Is It Dangerous To Take Creatine Supplement While Also Getting

default
Posted on Sun, 17 Jan 2021
Question: Is it dangerous to take creatine supplement while also getting PEG through smokeless cigarettes or medications? Creatine is used by body builders to help work muscles extra hard. It enhances cellular metabolic activity, but not too much, because it's not very soluble. But what if PEG solvent is in the body also? Could the solvent increase the amount of creatine absorbed to the point that there might be dangerously too much artificial stimulation of cellular metabolic activity? Is there any record of body builders getting into medical trouble of this kind?
A reference is at http://www.medicalveritas.com/manAlBayatiChuck.pdf
doctor
Answered by Dr. Dr. Matt Wachsman (1 hour later)
Brief Answer:
probably wrong.

Detailed Answer:
Ethylene glycol is dangerous by itself. Mixing it with something else is like saying. "gee the guy had a red tie on when he was shot...there's all this red on him.. maybe the tie interacted with the gunshot". Yeah, it's fatal, but not due to what it is mixed with.
no.
Ethylene glycol:
breaks down to ketones... check
solubilized bloood................check
damages the kidneys...........check
The article's main point is... the main point. Ethylene glycol breaks down to ketones and lactate and other organic acids which were found and could do everything mentioned. Methanol IS ONE CARBON. Lactate and ketones are MORE THAN ONE CARBON and you can't get there from methanol. Methanol forms formic acid (one carbon) and they needed to check for it to say methan0l poisoned him. All the multicarbon acids--ketones and lactate cannot come from a ONE carbon poison (methanol).
ALso, giving bicarb lowers the acidity of the BLOOD but the bicarb goes into the brain and is reconverted back into acid and is a typical beginner fatal beginning intern ICU mistake .. mostly on Board exams and almost never in reality because they'd be on a ventilator and overventilation pullls out acidity.. and also methanol.
I am not finding a single report of creatine overdose toxicity. Indeed 20 grams is standard and certainly 30 gram is not dangerous with daily dosing. It's hard to see how it could do these things. It is a component of muscle--both in food (meat) and in muscle. It is soluble. It gets filtered out. Eating more meat doesn't overstimulate metabolism and neither would eating more nutrients. It just doesnt' work that way.

and EthyleneGlycol is a notorious toxin--antifreeze.
https://abcnews.go.com/US/wife-charged-attempted-murder-allegedly-poison-husband-antifreeze/story?id=0000
Two points on POLYethylene glycol. It is big and doesn't get in that much and its toxicity has stoichiometry.... you need tablespoons of the right stuff to be dangerous, and you get only the amount of breakdown products of ethyene glycol proportional to what you put in. You can't get more breakdown than the amount of the thing that breaks down. That just isn't possible. smoking it can't get several tablespoons in. AND PEG isn't the right stuff.
Note: In case of any other concern or query related to prevention, evaluation, diagnosis, treatment, or the recovery of persons with the any type of addiction or substance use, follow up with our Addiction Medicine Specialist. Click here to book a consultation now.

Above answer was peer-reviewed by : Dr. Raju A.T
doctor
Answered by
Dr.
Dr. Dr. Matt Wachsman

Addiction Medicine Specialist

Practicing since :1985

Answered : 4214 Questions

premium_optimized

The User accepted the expert's answer

Share on

Get personalised answers from verified doctor in minutes across 80+ specialties

159 Doctors Online

By proceeding, I accept the Terms and Conditions

HCM Blog Instant Access to Doctors
HCM Blog Questions Answered
HCM Blog Satisfaction
Is It Dangerous To Take Creatine Supplement While Also Getting

Brief Answer: probably wrong. Detailed Answer: Ethylene glycol is dangerous by itself. Mixing it with something else is like saying. "gee the guy had a red tie on when he was shot...there's all this red on him.. maybe the tie interacted with the gunshot". Yeah, it's fatal, but not due to what it is mixed with. no. Ethylene glycol: breaks down to ketones... check solubilized bloood................check damages the kidneys...........check The article's main point is... the main point. Ethylene glycol breaks down to ketones and lactate and other organic acids which were found and could do everything mentioned. Methanol IS ONE CARBON. Lactate and ketones are MORE THAN ONE CARBON and you can't get there from methanol. Methanol forms formic acid (one carbon) and they needed to check for it to say methan0l poisoned him. All the multicarbon acids--ketones and lactate cannot come from a ONE carbon poison (methanol). ALso, giving bicarb lowers the acidity of the BLOOD but the bicarb goes into the brain and is reconverted back into acid and is a typical beginner fatal beginning intern ICU mistake .. mostly on Board exams and almost never in reality because they'd be on a ventilator and overventilation pullls out acidity.. and also methanol. I am not finding a single report of creatine overdose toxicity. Indeed 20 grams is standard and certainly 30 gram is not dangerous with daily dosing. It's hard to see how it could do these things. It is a component of muscle--both in food (meat) and in muscle. It is soluble. It gets filtered out. Eating more meat doesn't overstimulate metabolism and neither would eating more nutrients. It just doesnt' work that way. and EthyleneGlycol is a notorious toxin--antifreeze. https://abcnews.go.com/US/wife-charged-attempted-murder-allegedly-poison-husband-antifreeze/story?id=0000 Two points on POLYethylene glycol. It is big and doesn't get in that much and its toxicity has stoichiometry.... you need tablespoons of the right stuff to be dangerous, and you get only the amount of breakdown products of ethyene glycol proportional to what you put in. You can't get more breakdown than the amount of the thing that breaks down. That just isn't possible. smoking it can't get several tablespoons in. AND PEG isn't the right stuff.