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Is It Possible That 3 Months Of Injections Could Have Made My Brain Sensitive To Meth And I Ended Up Killing Off My Dopamine Receptors With My Concurrent Meth Use?

Posted on Wed, 22 Mar 2023

Question: .Is it possible that 3 months of injections could have made my brain sensitive to meth and I ended up killing off my dopamine receptors with my concurrent meth use? Because now when I smoke meth it feels like a warm XXXXXXX migraine like feeling with ringing ears. I can only barely feel high, and when I get my heart rate up it seems to sober me up almost instantly even skipping the comedown.
I don't know if it's a side affect of the invega in my blood rushing to my head or if my dopamine receptors are activating then shutting down due to the excess dopamine. I need help on this bad. I don't want to kill my receptors. I don't know what to do. And if it is the receptors I don't know how long I gotta let them heal or what. I wanna be able to get high in the future but am scared of what's going on.

Answered by Dr. Neeraj Kumar (3 hours later)

Brief Answer:
Stop use to rejuvenate receptors

Detailed Answer:
Hello,
I have gone through your question and understand your concern.
Use of any drug or substance of abuse leads to increased metabolism of substance with habituation.
Ultimately, the same dose may not be giving the effect as earlier.
Stopping for few months leads to improvement in receptor.
Substance abuse has its own side effects and need to be consulted with deaddiction clinic.
Regards
Dr N Kumar
Neurologist

Above answer was peer-reviewed by : Dr. Yogesh D

Follow up: Dr. Neeraj Kumar (47 minutes later)

Do u think I killed my receptors? If I did will new ones grow?

Answered by Dr. Neeraj Kumar (14 hours later)

Brief Answer:
Gradually improvement will occur after cessation

Detailed Answer:
Hello,
There is definitely damage to receptor and cessation of substance will gradually heal it.
Regards
Dr N Kumar
Neurologist

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Neeraj Kumar (1 hour later)

How long should I give it to heal?

Answered by Dr. Neeraj Kumar (13 hours later)

Brief Answer:
Approximately 3-6 months

Detailed Answer:
Hello,
Approximately 3-6 months for healing.
Regard
Dr N Kumar

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Neeraj Kumar (15 hours later)

Do dopamine receptors shut down to repair themselves?

Answered by Dr. Neeraj Kumar (17 hours later)

Brief Answer:
Other receptors keep on working

Detailed Answer:
Hello,
There are many receptors and few are working at a time and others are used when required.
Similarly repairing process also occurs in damaged receptor.
Regards
Dr N Kumar
Neurologist

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Neeraj Kumar (13 days later)

So I was high the other night and went sober then high then sober completely and my ears have not stopped ringing since. That was 3 nights ago

Answered by Dr. Neeraj Kumar (20 hours later)

Brief Answer:
Get examined by a neurologist or ENT specialist

Detailed Answer:
Hello,
You should get examined by a Neurologist for any possibility of vertigo or tinnitus.
Regards
Dr N Kumar
Neurologist

Above answer was peer-reviewed by : Dr. Prasad

Follow up: Dr. Neeraj Kumar (3 hours later)

Is it possible to kill your dopamine receptors and make it so I will never get high on meth again?

Answered by Dr. Neeraj Kumar (17 hours later)

Brief Answer:
Receptors rejuvenate with time

Detailed Answer:
Hello,
Usually it is not the case with chronic intake.
Receptors rejuvenate again with stoppage of exposure.
Regards
Dr N Kumar
Neurologist

Above answer was peer-reviewed by : Dr. Nagamani Ng