Is Neck Thickening From Prolonged Prednisone Use,reversible?

Brief Answer: It is but slowly and gradual with no cause behind Detailed Answer: Thank you for asking! This neck thickening is called a Buffalo hump and is a very common result of prolonged use of prednisone. It is a presentation of cushing's disease / syndrome and it needs an endocrinologist for helping with this hormonal imbalances.Now whether it is reversible or not will be addressed by its extent of derangement. Higher levels of hypercortisolism takes time and a lot of effort.management of exogenous hypercortisolism involves optimization of glucocorticoid dose and route and use of glucocorticoid-sparing agents to minimize the glucocorticoid dose. replacement therapy with hydrocortisones to manage HPA axis and adrenal insufficiency is necessary. Use high-protein, calorie-restricted diet that is rich in potassium, calcium, and vitamin D and is low in sodium.If evidence of significant insulin resistance is present, carbohydrate intake may also need modification. Lose weight and hormonal axis will be back to normal and buffalo neck will go away but it wont happen in a day. The reason for all this has been prednisone. So it needs to be stopped. And replacement of it with an expertise of an endocrinologist will for sure reverse the trouble but it will take time. So hang in there and do as directed by your endocrinologist. I hope it helps.Dont forget to close the discussion please. May the odds be ever in your favour. S Khan

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