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Is Negative DUO CMIA HIV Test After 4 Weeks Of Exposure Conclusive?
Question: Respected sir...feb 19 i had unprotected sex(veginal)....after 3 days i have hiv symotoms.(fever,body pain,tried)...so i tested (march 3rd) (pcr real time qualitative viral load test)..that test result is target is undetected 40ml..and i tested all std related test all are negative but my seman test is ecoli bacteria seen.also uti......so 14 days my doc pref antibiotic......same march 3rd i tested anti hiv cmia test...that test result is non reactive(0.11)..after march 10 (20 days xposure) p24 antigen test..thats also negative sir.....after march 26th(5 weeks) i tested anti hiv clia test..thats negative but value(0.36)...that same day i tested western blot antibody test....thats negative only sir......next day i tested 4th generation duo cmia test...that test also negative..but ref value(0.89) sir borderline...that only iam very worried sir..still now i have hiv symptoms Sir...
Brief Answer:
Test values have no importance, only to know negative or positive
Detailed Answer:
Hi,
Welcome to HCM.
Thanks for posting your query.
There is nothing serious to be worried.
Earliest HIV manifestations can occur only 50-70% of the infected individuals and not with all, that too, these symptoms can occur only after 3-4 weeks and not earlier. So the symptoms of fever. Body pain and tiredness occurring to you 3 days after the contact,have nothing to do with HIV. Such symptoms can occur to anybody without HIV, that too, following a close intimacy with some body who has a throat infection or a cold.
Regarding your tests , those (4th generation DUO CMIA) done after 4 weeks after the high risk contact, clearly ruled out the possibility of HIV 1 infection. The antigen part is conclusive after 4 weeks (even though antigen can be detected from the first week on wards). Antibody part of the test can be reliable only after 8-12 weeks (after the window period) including the western Blot test.
You need not bother about the values of the test reading. It is enough that the reading is below the 'cut off' value for that test indicated by the manufacturer of the product. There is nothing like strong negative or borderline negative etc.
HIV 1 infections prevalence is little above 99% whereas HIV 2 is less than 1%.
So you need not worry about that For your symptom follow the advice of your physician.
Dr S.Murugan
Test values have no importance, only to know negative or positive
Detailed Answer:
Hi,
Welcome to HCM.
Thanks for posting your query.
There is nothing serious to be worried.
Earliest HIV manifestations can occur only 50-70% of the infected individuals and not with all, that too, these symptoms can occur only after 3-4 weeks and not earlier. So the symptoms of fever. Body pain and tiredness occurring to you 3 days after the contact,have nothing to do with HIV. Such symptoms can occur to anybody without HIV, that too, following a close intimacy with some body who has a throat infection or a cold.
Regarding your tests , those (4th generation DUO CMIA) done after 4 weeks after the high risk contact, clearly ruled out the possibility of HIV 1 infection. The antigen part is conclusive after 4 weeks (even though antigen can be detected from the first week on wards). Antibody part of the test can be reliable only after 8-12 weeks (after the window period) including the western Blot test.
You need not bother about the values of the test reading. It is enough that the reading is below the 'cut off' value for that test indicated by the manufacturer of the product. There is nothing like strong negative or borderline negative etc.
HIV 1 infections prevalence is little above 99% whereas HIV 2 is less than 1%.
So you need not worry about that For your symptom follow the advice of your physician.
Dr S.Murugan
Above answer was peer-reviewed by :
Dr. Shanthi.E
Thank you so much for your replyy sir....myy doctor also told hiv is clearly ruled out...also that ttiredness fever mayy be occur that anxity and uti infecttion.also u taken very heavy antibiotic(magnes fort3g injection morning and night)...also doxy 100 tab also....that affect also may occur...hiv is ruled out..but your satifaction...8th week..that means (march 17)..he told u will tested again(for my satisfaction only)..(duo test)....sir....that test resultt is will chances to change sir?..
Brief Answer:
Your symptoms were clearly not due to HIV.
Detailed Answer:
Hi,
Welcome back.
As your doctor told the symptoms were not related to HIV disease.
Regarding the test, it is better to have the final test after 12 weeks instead of 8 weeks as there is no possibility of sero- conversion after that period. As your test ruled out totally the possibility of HIV 1 infection, the chances of HIV due to that contact is almost nil to the extent of 99.5%.
So you need not worry much about the result of the future test.
Dr S.Murugan
Your symptoms were clearly not due to HIV.
Detailed Answer:
Hi,
Welcome back.
As your doctor told the symptoms were not related to HIV disease.
Regarding the test, it is better to have the final test after 12 weeks instead of 8 weeks as there is no possibility of sero- conversion after that period. As your test ruled out totally the possibility of HIV 1 infection, the chances of HIV due to that contact is almost nil to the extent of 99.5%.
So you need not worry much about the result of the future test.
Dr S.Murugan
Above answer was peer-reviewed by :
Dr. Shanthi.E
Thank uu so much doctor sir...you gived the excellent detail sirr.now only i feel better....
Brief Answer:
Welcome. Feel free to ask at anytime.
Detailed Answer:
HI,
You are most welcome. If you have any more queries feel free to ask. In case there is no more questions to ask at present you can close this conversation.
Dr S.Murugan
Welcome. Feel free to ask at anytime.
Detailed Answer:
HI,
You are most welcome. If you have any more queries feel free to ask. In case there is no more questions to ask at present you can close this conversation.
Dr S.Murugan
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Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar
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