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Is Rabies Re-vaccination Required When Antibody Titer Is Above Normal Level?

Posted on Mon, 14 Sep 2015

Question: Hello I went for my antibody test for rabies and its outcome is 1.12iu/ml I have taken pre exposure on 0 3 7 days?sir now my question is that if any one antibody titre is above the normal level and he's immunised then if if if virus attack someone who's antibody is more than required then he's safe this question is for any vaccine?if abtibody measured above normal level then that antibody neutralise the virus?

Answered by Dr. Vivek Chail (14 minutes later)

Brief Answer:
The virus is neutralized if antibody titre is more than required

Detailed Answer:
Hi XXXX,
Thanks for writing in to us.

I have read through your query in detail.
Please find my observations below.

1. In continuity with your earlier discussion the antibody titre is 1.12 IU/ ml which is above 0.5 IU/ ml.

2. Therefore your antibody titre is more than double the required amount.

3. If any one is having antibody titre like you and is attacked by the rabies virus then the infection will be neutralized and the person is safe. This is for any vaccine.

Please feel free to correct any oversight in my interpretation of your problems and discuss them in detail as per your requirements.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Vivek Chail (3 minutes later)

Sir just for knowledge I'm asking this question as I'm a vetenarian if the person gets attacked on face or neck and his antibody level is more than required or more than that then also he's safe asking for rabies vaccine?

Answered by Dr. Vivek Chail (9 minutes later)

Brief Answer:
Vaccine booster and rabies immune globulin is better in this situation

Detailed Answer:
Hi XXXX,
Thanks for writing back with an update.

1. If there is attack on the face or neck then it becomes a high grade of exposure. In this situation vaccine with booster dose is recommended even if antibodies are more than required. To be completely safe administration of rabies immune globulin is recommended in these patients if there is severe injury.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Vivek Chail (17 minutes later)

Sir I also want to know one more question of anything bites then it's hurt as usual if bat bite then also it pain or not and blood will come out?and sir its for surety said that if antibody level is more than recommended than person is safe?

Answered by Dr. Vivek Chail (7 minutes later)

Brief Answer:
If antibody is higher than required then person is absolutely safe

Detailed Answer:
Hi XXXX,
Thanks for writing back with an update.

1. Bat bites are difficult to notice sometimes.

2. Bats might scratch or bite and it is superficial.

3. If antibody is higher than required then the person is absolutely safe.

Hope your query is answered.
Do write back if you have any doubts.

Regards,
Dr.Vivek

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar