
Is There A Link Between Hives And Hormone Changes?

Hives are due to allergy; not to hormonal changes
Detailed Answer:
Hi Ms XXXXX,
Good Day to you,
I have gone through your query and understand your concerns.
* There is no known correlation between onset of hives with hormonal changes.
* You have not mentioned if diagnostic tests were done which confirmed the diagnosis of Autoimmune Urticaria.
* If it is a confirmed diagnosis, treatment is a daunting task, as response to conventional anti-allergic drugs is variable or even disappointing. I have, however, had a few patients in clinic, who have shown favorable response to unconventional doses of Fexofenadine 120mg twice daily.
* Oral steroids are quite effective, but- given their side effects- they are recommended in short courses during severe attacks.
* Further, your symptoms such as weight gain, lethargy, mood swings, migraines, easy fatigability and lethargy point towards co-existing Hypothyroid state. I recommend that you get a Thyroid Hormonal assay done to exclude/confirm the diagnosis. Another test- Anti-TPO antibodies (which indicates autoimmune hypothyroidism), if positive, will lend further credence to the diagnosis of Autoimmune Urticaria.
* Nevertheless, there is a possibility that you may be allergic to medicines such as pain-killers, which I presume, you might be taking for migraines. Try stopping pain-killers and see the response.
Under the circumstances, I suggest that you discuss the entire matter with your treating doctor who, in his wisdom, may
- order Thyroid hormonal assay test. If it indicates Hypothyroidism, he will prescribe Thyroid hormonal replacement therapy- which will take care of problems other than hives.
- prescribe other anti-allergic medicines, in combination (anti-histaminics, montelukast, azelastine nasal spray; inhaled bronchodilators + steroids for asthma.
* If there is no significant response to these agents, your doctor may consider using appropriate anti-cancer drugs to curb hives. Or, may even contemplate giving a trial of intravenous immunoglobulins (synthetic antibodies).
* You should also go in for long-term preventive treatment for Migraine. your doctor would know the appropriate drugs.
Hope I have addressed your query to your satisfaction. If you have any further questions, I will be more than happy to help you.
However, if you do not have any further clarifications, you can close the discussion and rate the answer.
Wish you a speedy recovery and good health.
Fond regards and best wishes,
Dr. (Col) R Karanwal

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