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Is There Any Correlation Between A Oral Rash And An EBV Infection?

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Posted on Wed, 26 Oct 2016
Question: Hi
Have crack down the center of my tongue for years. I have been tested and have /had
EBV. So somewhere googling I found there seemed like there was a connection between EBV and chronic crack in the tongue.
Is there a connection?
Oh the main reason I am concerned about understanding the cracked tongue and EBV is that for years I have a irritated throat on my left side when I get fatigued. Concerned this could turn into thyroid cancer. I recently developed a slight internal lump on the left side of my neck.
doctor
Answered by Dr. Shehzad Topiwala (32 minutes later)
Brief Answer:
Tests

Detailed Answer:
Sorry to learn about your bothersome symptoms.

1 EBV can lead to an oral rash due to OHL (Oral Hairy Leukoplakia). Please get yourself examined for this possibility

2 Regarding thyroid, the best way to see if there is a lump in the neck originating from the thyroid gland is to do a Neck Ultrasound.

When I see someone like you in my practice, I typically order the following blood tests in addition to a detailed physical examination:

CBC (Complete Blood Count, also known as Hemogram; includes Hemoglobin, WBC and Platelet counts)
Electrolytes (Sodium and Potassium in particular)
HbA1c (Glycosylated Hemoglobin = your last 3 months' glucose average). Also known by other names such as GlycoHemoglobin or Glycated Hemoglobin or A1c
Liver function tests (SGOT , SGPT, Albumin, Bilirubin, Alkaline Phosphatase)
Kidney function tests (BUN, Creatinine)
TSH (checks your thyroid)
Free T4 (this too checks your thyroid) Thyroid autoantibodies : Anti Thyroid Peroxidase (TPO) antibodies and Anti Thyroglobulin antibodies
25 hydroxy Vitamin D levels (ideal range 40 to 60 ng/ml = 100 to 150 nmol/liter)

None of these tests require any fasting and can be done at any time of the day Correct diagnosis and treatment requires the opportunity to examine the patient so you must see an endocrinologist in-person.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Shehzad Topiwala (37 hours later)
Hi
Thank you for your information I keep regular check ups and I will have those test done
The OHL if it's proven I have it what what the usual treatment for it
Thanks
doctor
Answered by Dr. Shehzad Topiwala (8 hours later)
Brief Answer:
Follow up

Detailed Answer:
Sometimes it is not treated and on other occasions medications like topical podophyllin or isotretinoin are used. The dermatologist will guide you
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Shehzad Topiwala (40 hours later)
Hi

Two Questions:

(1) Would it be a possibility that OHL could be helped internally if stem cells decreased Langerhans cells?

The Langerhans cells are antigen-presenting immune cells that are required for an immune system response to the viral infection and their deficiency may permit EBV to persistently relocate and escape immune recognition.

Medscape :
1. Virus enters B Cells
2. Cytotoxic T Lymphocytes cannot eliminate EBV- but are essential in maintaining latent infection.
3. In states of immune dysfunction which some EBV-specific cytotoxic T lymphocytes is decreased - there is an increase in the number of circulating EBV- infected B cells.
4.In addition a marked decrease on the absence of Langerhans cells occurs in OHL tissue.

(2) But if the Langerhans cells are decreased (by infusion of my own stem cells) and the EBV is not recognized causing the EBV not to take effect - what is the loss to my system to have fewer Langerhans cells?

Thanks
XXXX
doctor
Answered by Dr. Shehzad Topiwala (7 hours later)
Brief Answer:
Second follow up

Detailed Answer:
1 This, to my knowledge, is not an established fact

2 This too as of now, to the best of my knowledge, is not known
Note: For more information on hormonal imbalance symptoms or unmanaged diabetes with other comorbid conditions, get back to us & Consult with an Endocrinologist. Click here to book an appointment.

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
Answered by
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Dr. Shehzad Topiwala

Endocrinologist

Practicing since :2001

Answered : 1663 Questions

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Is There Any Correlation Between A Oral Rash And An EBV Infection?

Brief Answer: Tests Detailed Answer: Sorry to learn about your bothersome symptoms. 1 EBV can lead to an oral rash due to OHL (Oral Hairy Leukoplakia). Please get yourself examined for this possibility 2 Regarding thyroid, the best way to see if there is a lump in the neck originating from the thyroid gland is to do a Neck Ultrasound. When I see someone like you in my practice, I typically order the following blood tests in addition to a detailed physical examination: CBC (Complete Blood Count, also known as Hemogram; includes Hemoglobin, WBC and Platelet counts) Electrolytes (Sodium and Potassium in particular) HbA1c (Glycosylated Hemoglobin = your last 3 months' glucose average). Also known by other names such as GlycoHemoglobin or Glycated Hemoglobin or A1c Liver function tests (SGOT , SGPT, Albumin, Bilirubin, Alkaline Phosphatase) Kidney function tests (BUN, Creatinine) TSH (checks your thyroid) Free T4 (this too checks your thyroid) Thyroid autoantibodies : Anti Thyroid Peroxidase (TPO) antibodies and Anti Thyroglobulin antibodies 25 hydroxy Vitamin D levels (ideal range 40 to 60 ng/ml = 100 to 150 nmol/liter) None of these tests require any fasting and can be done at any time of the day Correct diagnosis and treatment requires the opportunity to examine the patient so you must see an endocrinologist in-person.