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Is There Anything That Can Reduce Hot Flashes Due To Lupron Injections?

Posted on Fri, 22 Jan 2021

Question: is there anything that can reduce hot flashes from Lupron injections? My husband suffers terribly from them, affecting his sleep, which he already had trouble with. Any help would be appreciated. XXXXXXX Moris

Answered by Dr. Deepak Sundriyal (15 minutes later)

Brief Answer:
Hello. Venlafaxine can be used

Detailed Answer:
Hello dear. I understand your concern. Hot flashes are a common side effects of anti-hormonal therapies but they tend to diminish with increasing duration of therapy. However, if they are really troublesome, you can use venlafaxine which is a selective norepinephrine uptake inhibitor drug. This helps to mitigate hot flashes and elevates mood.
Please consult your doctor for a prescription.
Thanks and regards
Feel free to ask further

Above answer was peer-reviewed by : Dr. Nagamani Ng

Follow up: Dr. Deepak Sundriyal (24 hours later)

Thanks for your answer. Since he's decided to do intermitant therapy, its been four months since he's had a shot. Does going off Lupron make the hot flashes worse or will they decline the longer he goes without a shot?
Thanks, XXXXXXX

Answered by Dr. Deepak Sundriyal (1 hour later)

Brief Answer:
Hello. They will decline

Detailed Answer:
Hello dear. So slowly the side effects of lupron wean off and they should decline with increasing interval. After some time , adaptation occur.
Thanks and regards

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Above answer was peer-reviewed by : Dr. Nagamani Ng