Hello,
Thanks for writing in.
Decreased libido is a common side effect of almost all the anti depressants. Currently they are most commonly associated with selective serotonin reuptake inhibitors.
The management of sexual dysfunction caused by anti-depressants involves many steps. However, the steps outlined below, need to be followed after consulting your treating physician. This is extremely important.
•     Schedule your daily dose right after the time you would normally expect to engage in sexual activity, when the drug's level in your body would be at its lowest.
•     Consult your physician and get your doses reduced to decrease the sexual side effects after consulting with your physician.
•     Schedule a two day drug holiday each week in order to restore sexual function without losing the efficacy of the antidepressant drugs. This may be useful if you are taking paroxetine or sertraline, but not with other drugs.
•     Ask your physician about changing your medication. Certain anti-depressants have lesser sexual side effects.
•     There are several drugs which can act as potential antidotes. These include amantadine, bethanechol, bromocriptine, bupropion, cyproheptadine, dextroamphetamine, ginkgo biloba, granisetron, loratadine, methylphenidate, , mirtazapine, nefazodone, neostigmine, pemoline, pramipexole, ropinirole and trazodone. These are prescription drugs and treatment would need to be customized to the patients. Please see your treating physician for the same.

I hope I have addressed your concerns. I will be available for follow ups. Please close this discussion if you have no further questions
Regards.
Dr. Rakhi Tayal.

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