Lung Cancer Stage 4, COPD. Soft Tissue Mass On Chest Plate. General Treatment?
The adenosquamous carcinoma is a rare combined tumour of non-small cell lung cancer and patients who had been treated only surgically have poor survival prognosis and ask for an adjuvant therapy.
Because unfortunately we speak about an advanced disease, the drug regimen with the highest likelihood of benefit with toxicity deemed acceptable to both the physician and the patient should be given.
Has your husband done molecular diagnostic studies to determine whether certain gene mutations are present? If yes, please let me know the results.
If no, he should and until then Bevacizumab + chemotherapy is indicated in performance status 0-1 patients. Platinum-based chemotherapy is the best one because prolongs survival, improves symptom control and yields superior quality of life compared to best supportive care.
To determine his performance status, please let me know if he is completely ambulatory, so he is able to carry out work of a light or sedentary nature or he is unable to carry out any work activities.
Regarding his chances of surviving this, I am afraid they are very low, statistically the overall 5-year survival rate is less than 10%.
If you have any more queries, feel free to ask.
Regards
Dr. Dorian Oana MD, PhD
Not sure. I know they did a biopsy of fluid and lining. Have not recieved the report yet.
He is able to walk around bit with oxygen but has to pace himself. otherwise he gets labored breathing.
Is there anything specific I should be asking the oncologist tomorrow when he see him?
Thanks for your reply.
Yes, you should ask him first about the molecular diagnostic.
On the other hand, you should ask him if he considers right to wait until the performance status of the patient improves a little before starting chemotherapy or he thinks he should start it as soon as possible, even if with a less aggressive chemotherapy.
If you have any more queries, feel free to ask.
Regards
Dr. Dorian Oana MD, PhD
Is there any clinical trails that work well with adenosquamous stage 4 lung cancer?
Thanks for your reply.
There are clinical trails that work with adenosquamous stage 4 lung cancer. I give you below two examples:
1. Docetaxel, Cisplatin, Pegfilgrastim, and Erlotinib Hydrochloride in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
2. Gemcitabine Hydrochloride and Carboplatin With or Without MK-0646 as First-Line Therapy in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung Cancer
You should discuss with Dr. Silberberg these opportunities before starting any chemotherapy, because these two examples of clinical trials have like inclusion criteria: More than 12 months since prior gemcitabine hydrochloride, cisplatin, or carboplatin or No prior chemotherapy.
If you have any more queries, feel free to ask.
Regards
Dr. Dorian Oana MD, PhD
Thanks for your reply.
Unfortunately I am 100% this is not possible and it cannot work. Please be very careful because there are a lot offers like that online and you should not buy anything without oncologist's recommendation. This kind of websites just want to make money, with any risk and they are not reliable at all.
If you have any more queries, feel free to ask.
Regards
Dr. Dorian Oana MD, PhD