Mildly Elevated D Dimer For 2 Years, Lacy Pattern On

Posted on Tue, 7 May 2019

Question: Mildly elevated D dimer for 2 years, lacy pattern on lower extremities, Dermatographism or mast cell activation(I was told 10 years ago that it was dermatographism) muscle pain, joint pain large and small and severe fatigue, blue screla. 5 years ago my ana and RNP were elevated but now normal, also my chromatin level stays elevated. sores on scalp, slightly low aldolase, slightly low creatine CK.
I am undignosed. Not sure what my next step should be.

Answered by Dr. Dr. Gopal (9 hours later)

Brief Answer:
Pl see details below

Detailed Answer:
Hi I am Dr Gopal Goel, Orthopedic Surgeon.
I have gone through the details and the pictures.
First of all this does not appear to be Dermatographism to me - In dermatographism we see raised skin ( only temporarily).
Blue sclera is suggestive of some connective tissue disorder like osteogenesis imperfecta, Marfan's syndrome, Ehlers-Danlos syndrome, pseudoxanthoma elasticum, and Willems De Vries syndrome, to begin with.
I can only suggest symptomatic treatment like pain killers SOS . Get blood levels of Vitamin B12 and D3 to see if any deficiency disease is present.
I am afraid not much can be discussed about your condition. all the above I have mentioned do not fit into your description.
I would suggest that you consult some rheumatologist ,who may be more helpful.
Thanks for the question. hope to hear from you soon with good news of definitive diagnosis .

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Above answer was peer-reviewed by : Dr. Yogesh D