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My TSH Level Is High With ANTI MICROSOMAL ANTIBODY (AMA) Should I Be Worried

Posted on Wed, 10 Jan 2024

Question: My TSH level is high, latest report shows 8.5 as of 4th Dec, (has been high in most tests I have done in least few years with one or two times of exception when its normal) with normal T3 (185) and T4(7.88). Doc asked for Anti TPO test. As per results ANTI MICROSOMAL ANTIBODY (AMA) value is 326.3 IU/mL What should I do in this case

Answered by Dr. Dr.Raju.A.T (9 hours later)

Brief Answer:
Need some more details

Detailed Answer:
Hi,

Thanks for your query

I have gone through the report

AMA, RA factor, ESR, CRP all are raised indicating autoimmune thyroiditis, this requires management with steroids if you are symptomatic or your TSH is too high.

Do you have any symptoms like weight gain, joint pains, hair lose, excess fatigue, thyroid swelling, swelling in feet or face etc ?

What is the Thyroxine dosage you are on ?

Waiting for your response

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Dr.Raju.A.T (11 hours later)

I am currently on no medication. I had thyronorm 25mcg during pregnancy (4ys back) and once based on a docs input for 3 months earlier this year.

Symptoms are mostly overall low energy, excessive fatigue, irritability and anxiety.

Recently since past few months I have started having pain in joints but its shifting and non consisitent. Like it may happen once a month or twice for a few day and during these sessions each day a new joint is affected. Like it once started with my mandibular joint. i could hardly open my mouth to eat anything, next day it automatically shifted to my right wrist, next to a finger and then left shoulder joint and then gone. it comes back again after 15-20 days and shifts between a few joints, mostly finger and wrist and goes of it own. while it lasts its very painful for the affected joint with light swelling and warm feeling in the area.

Answered by Dr. Dr.Raju.A.T (2 days later)

Brief Answer:
Thyroid hormone status

Detailed Answer:
Hi,

Thanks for writing back

When was the last time you got your thyroid hormone status checked

If you have, please share the report

Waiting for your response

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Dr.Raju.A.T (2 days later)

5th Dec 2023: TSH 8.5/ T3 185/ T4 7.88

12th Aug 2023: TSH 5.27/ T3 105/ T4 8.51

24th Feb 2033: TSH 5.15/ T3 1.25 ng/ml/ T4 11.31 ug/ml

7th XXXXXXX 2022: TSH 7.50/ T3 90 / T4 7.1

29th Dec 2020: TSH 7.52/ T3 96 / T4 7

Answered by Dr. Dr.Raju.A.T (12 hours later)

Brief Answer:
Need medication

Detailed Answer:
Hi,

Thanks for your response

Need to start low dose (25mcg) Thyronorm.

If you have any pain or swelling in the thyroid gland, you must be started on steroids.

Regards,

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Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar