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My Brother Is Diagnosed With High Grade Invasive Pt1 Bladder

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Posted on Sat, 12 Dec 2020
Question: My brother is diagnosed with High grade invasive Pt1 bladder cancer. His urologist decided to do BCG injection. Is that treatment is beneficial for him?
in the CT report,
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Follow up: Dr. Indranil Ghosh (0 minute later)
My brother is diagnosed with High grade invasive Pt1 bladder cancer. His urologist decided to do BCG injection. Is that treatment is beneficial for him?
in the CT report,
doctor
Answered by Dr. Indranil Ghosh (3 hours later)
Brief Answer:
Yes BCG is recommended

Detailed Answer:
Hi
Thanks for your query.

As it is high grade pt1 disease, intravesical BCG is definitely recommended. It helps reduce the risks for recurrence.

However, in high grade pT1, another check cystoscopy is recommended before BCG, as it can pick up residual disease which can also be resected. This also reduces the possibility of missing muscle invasive disease because it requires removal of bladder.

Hope this helps.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
doctor
Answered by Dr. Indranil Ghosh (0 minute later)
Brief Answer:
Yes BCG is recommended

Detailed Answer:
Hi
Thanks for your query.

As it is high grade pt1 disease, intravesical BCG is definitely recommended. It helps reduce the risks for recurrence.

However, in high grade pT1, another check cystoscopy is recommended before BCG, as it can pick up residual disease which can also be resected. This also reduces the possibility of missing muscle invasive disease because it requires removal of bladder.

Hope this helps.
Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Indranil Ghosh (6 hours later)
He had TURBT 10/26/20 and 11/13/20 twice, and now he is complicated with bleeding on 8th POD of 2nd TURBT. Bleeding might be caused by infection or disease progression. BCG treatment postponed to 12/3/2020. Because of delaying treatment, will the disease progress more.
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Follow up: Dr. Indranil Ghosh (0 minute later)
He had TURBT 10/26/20 and 11/13/20 twice, and now he is complicated with bleeding on 8th POD of 2nd TURBT. Bleeding might be caused by infection or disease progression. BCG treatment postponed to 12/3/2020. Because of delaying treatment, will the disease progress more.
doctor
Answered by Dr. Indranil Ghosh (50 minutes later)
Brief Answer:
No I don't think it will progress so soon

Detailed Answer:
As already two TURBT done, no need of further TURBT. We can proceed to BCG after bleeding settles.

I don't think disease will progress so soon because of this short delay.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
doctor
Answered by Dr. Indranil Ghosh (0 minute later)
Brief Answer:
No I don't think it will progress so soon

Detailed Answer:
As already two TURBT done, no need of further TURBT. We can proceed to BCG after bleeding settles.

I don't think disease will progress so soon because of this short delay.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Indranil Ghosh (12 minutes later)
In his CT report, "it is mentioned as wall invasion with adjacent perivesical fat stranding and seen subcentrimetric paraaortic and bilateral iliac group of lymph nodes"

Do you think any lymph node involvement there? Do we need to do PET scan or whole body MRI to identify cancer /lymph node enlargement elsewhere in the body?

What are the things he need to follow when he takes BCG intravesically? He is urinating currently every 30 min.
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Follow up: Dr. Indranil Ghosh (0 minute later)
In his CT report, "it is mentioned as wall invasion with adjacent perivesical fat stranding and seen subcentrimetric paraaortic and bilateral iliac group of lymph nodes"

Do you think any lymph node involvement there? Do we need to do PET scan or whole body MRI to identify cancer /lymph node enlargement elsewhere in the body?

What are the things he need to follow when he takes BCG intravesically? He is urinating currently every 30 min.
doctor
Answered by Dr. Indranil Ghosh (8 hours later)
Brief Answer:
Doesn't look like significant lymph nodes

Detailed Answer:
Lymph node spread and extravesical extension is possible only in muscle invasive disease. Here there's no muscle invasion.

The lymph nodes mentioned in the report are too small and may not be involved by disease.

The perivesical extension on CT may sometimes be due to inflammation around the tumor.

PET CT is not beneficial in this type of bladder cancer. MRI may be of some benefit but after TURBT it will show many inflammatory changes.

If in doubt, another cystoscopy and biopsy to rule out muscle invasive disease can be done.

Regards
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
doctor
Answered by Dr. Indranil Ghosh (0 minute later)
Brief Answer:
Doesn't look like significant lymph nodes

Detailed Answer:
Lymph node spread and extravesical extension is possible only in muscle invasive disease. Here there's no muscle invasion.

The lymph nodes mentioned in the report are too small and may not be involved by disease.

The perivesical extension on CT may sometimes be due to inflammation around the tumor.

PET CT is not beneficial in this type of bladder cancer. MRI may be of some benefit but after TURBT it will show many inflammatory changes.

If in doubt, another cystoscopy and biopsy to rule out muscle invasive disease can be done.

Regards
Above answer was peer-reviewed by : Dr. Vaishalee Punj
doctor
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Follow up: Dr. Indranil Ghosh (3 hours later)
Thank you so much for all your answer. It's so much beneficial.
What are the things he need to follow when he takes BCG intravesically? How long He has to hold the urine? He is urinating currently every 30 min.
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Follow up: Dr. Indranil Ghosh (0 minute later)
Thank you so much for all your answer. It's so much beneficial.
What are the things he need to follow when he takes BCG intravesically? How long He has to hold the urine? He is urinating currently every 30 min.
doctor
Answered by Dr. Indranil Ghosh (19 hours later)
Brief Answer:
2hr holding ideal

Detailed Answer:
Less fluid intake before the procedure. After injection, 2 hr holding recommended. After passing urine, more fluid intake.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
doctor
Answered by Dr. Indranil Ghosh (0 minute later)
Brief Answer:
2hr holding ideal

Detailed Answer:
Less fluid intake before the procedure. After injection, 2 hr holding recommended. After passing urine, more fluid intake.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Indranil Ghosh (1 hour later)
Thank you. If he can't hold, will the medication be effective.
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Follow up: Dr. Indranil Ghosh (0 minute later)
Thank you. If he can't hold, will the medication be effective.
doctor
Answered by Dr. Indranil Ghosh (1 hour later)
Brief Answer:
partly effective

Detailed Answer:
Actually 30 min is too low. Hopefully it will improve by the time BCG is started.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
doctor
Answered by Dr. Indranil Ghosh (0 minute later)
Brief Answer:
partly effective

Detailed Answer:
Actually 30 min is too low. Hopefully it will improve by the time BCG is started.
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Indranil Ghosh (3 hours later)
Doctor, I am so much worried that's why I am asking so much questions. He is still bleeding. Whether is it complication or disease progression. I sent you the picture of his urine. Please suggest what we need to do. Urologist did ultrasound to identify whether he has clot. Please provide your suggestion.
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Follow up: Dr. Indranil Ghosh (0 minute later)
Doctor, I am so much worried that's why I am asking so much questions. He is still bleeding. Whether is it complication or disease progression. I sent you the picture of his urine. Please suggest what we need to do. Urologist did ultrasound to identify whether he has clot. Please provide your suggestion.
doctor
Answered by Dr. Indranil Ghosh (3 hours later)
Brief Answer:
It seems clot is there

Detailed Answer:
I understand.

There seems to be clot in the urine. I hope bladder irrigation is going on. If the problem persists, another cystoscopy will be required.

Progression of disease so early after TURBT is possible but rare. So let's take it as a complication of TURBT for now.
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
doctor
Answered by Dr. Indranil Ghosh (0 minute later)
Brief Answer:
It seems clot is there

Detailed Answer:
I understand.

There seems to be clot in the urine. I hope bladder irrigation is going on. If the problem persists, another cystoscopy will be required.

Progression of disease so early after TURBT is possible but rare. So let's take it as a complication of TURBT for now.
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Indranil Ghosh (1 hour later)
Thank you
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Follow up: Dr. Indranil Ghosh (0 minute later)
Thank you
doctor
Answered by Dr. Indranil Ghosh (1 hour later)
Brief Answer:
You are welcome

Detailed Answer:
If you don't have any more queries then please close this thread and give feedback.

Regards
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
doctor
Answered by Dr. Indranil Ghosh (0 minute later)
Brief Answer:
You are welcome

Detailed Answer:
If you don't have any more queries then please close this thread and give feedback.

Regards
Above answer was peer-reviewed by : Dr. Yogesh D
doctor
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Follow up: Dr. Indranil Ghosh (49 minutes later)
I don't have any questions now but if I need to ask any questions later, it will be easy for me if this thread is open. Since my brother is still in hospital and has symptoms.
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Follow up: Dr. Indranil Ghosh (0 minute later)
I don't have any questions now but if I need to ask any questions later, it will be easy for me if this thread is open. Since my brother is still in hospital and has symptoms.
doctor
Answered by Dr. Indranil Ghosh (10 hours later)
Brief Answer:
Ok

Detailed Answer:
sure
Above answer was peer-reviewed by : Dr. Kampana
doctor
doctor
Answered by Dr. Indranil Ghosh (0 minute later)
Brief Answer:
Ok

Detailed Answer:
sure
Note: For further queries related to kidney problems Click here.

Above answer was peer-reviewed by : Dr. Kampana
doctor
Answered by
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Dr. Indranil Ghosh

Oncologist

Practicing since :2004

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My Brother Is Diagnosed With High Grade Invasive Pt1 Bladder

My brother is diagnosed with High grade invasive Pt1 bladder cancer. His urologist decided to do BCG injection. Is that treatment is beneficial for him? in the CT report,