
My Brother Is Diagnosed With High Grade Invasive Pt1 Bladder

Question: My brother is diagnosed with High grade invasive Pt1 bladder cancer. His urologist decided to do BCG injection. Is that treatment is beneficial for him?
in the CT report,
in the CT report,

My brother is diagnosed with High grade invasive Pt1 bladder cancer. His urologist decided to do BCG injection. Is that treatment is beneficial for him?
in the CT report,
in the CT report,
Brief Answer:
Yes BCG is recommended
Detailed Answer:
Hi
Thanks for your query.
As it is high grade pt1 disease, intravesical BCG is definitely recommended. It helps reduce the risks for recurrence.
However, in high grade pT1, another check cystoscopy is recommended before BCG, as it can pick up residual disease which can also be resected. This also reduces the possibility of missing muscle invasive disease because it requires removal of bladder.
Hope this helps.
Regards
Yes BCG is recommended
Detailed Answer:
Hi
Thanks for your query.
As it is high grade pt1 disease, intravesical BCG is definitely recommended. It helps reduce the risks for recurrence.
However, in high grade pT1, another check cystoscopy is recommended before BCG, as it can pick up residual disease which can also be resected. This also reduces the possibility of missing muscle invasive disease because it requires removal of bladder.
Hope this helps.
Regards
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar

Brief Answer:
Yes BCG is recommended
Detailed Answer:
Hi
Thanks for your query.
As it is high grade pt1 disease, intravesical BCG is definitely recommended. It helps reduce the risks for recurrence.
However, in high grade pT1, another check cystoscopy is recommended before BCG, as it can pick up residual disease which can also be resected. This also reduces the possibility of missing muscle invasive disease because it requires removal of bladder.
Hope this helps.
Regards
Yes BCG is recommended
Detailed Answer:
Hi
Thanks for your query.
As it is high grade pt1 disease, intravesical BCG is definitely recommended. It helps reduce the risks for recurrence.
However, in high grade pT1, another check cystoscopy is recommended before BCG, as it can pick up residual disease which can also be resected. This also reduces the possibility of missing muscle invasive disease because it requires removal of bladder.
Hope this helps.
Regards
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar


He had TURBT 10/26/20 and 11/13/20 twice, and now he is complicated with bleeding on 8th POD of 2nd TURBT. Bleeding might be caused by infection or disease progression. BCG treatment postponed to 12/3/2020. Because of delaying treatment, will the disease progress more.

He had TURBT 10/26/20 and 11/13/20 twice, and now he is complicated with bleeding on 8th POD of 2nd TURBT. Bleeding might be caused by infection or disease progression. BCG treatment postponed to 12/3/2020. Because of delaying treatment, will the disease progress more.
Brief Answer:
No I don't think it will progress so soon
Detailed Answer:
As already two TURBT done, no need of further TURBT. We can proceed to BCG after bleeding settles.
I don't think disease will progress so soon because of this short delay.
Regards
No I don't think it will progress so soon
Detailed Answer:
As already two TURBT done, no need of further TURBT. We can proceed to BCG after bleeding settles.
I don't think disease will progress so soon because of this short delay.
Regards
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar

Brief Answer:
No I don't think it will progress so soon
Detailed Answer:
As already two TURBT done, no need of further TURBT. We can proceed to BCG after bleeding settles.
I don't think disease will progress so soon because of this short delay.
Regards
No I don't think it will progress so soon
Detailed Answer:
As already two TURBT done, no need of further TURBT. We can proceed to BCG after bleeding settles.
I don't think disease will progress so soon because of this short delay.
Regards
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar


In his CT report, "it is mentioned as wall invasion with adjacent perivesical fat stranding and seen subcentrimetric paraaortic and bilateral iliac group of lymph nodes"
Do you think any lymph node involvement there? Do we need to do PET scan or whole body MRI to identify cancer /lymph node enlargement elsewhere in the body?
What are the things he need to follow when he takes BCG intravesically? He is urinating currently every 30 min.
Do you think any lymph node involvement there? Do we need to do PET scan or whole body MRI to identify cancer /lymph node enlargement elsewhere in the body?
What are the things he need to follow when he takes BCG intravesically? He is urinating currently every 30 min.

In his CT report, "it is mentioned as wall invasion with adjacent perivesical fat stranding and seen subcentrimetric paraaortic and bilateral iliac group of lymph nodes"
Do you think any lymph node involvement there? Do we need to do PET scan or whole body MRI to identify cancer /lymph node enlargement elsewhere in the body?
What are the things he need to follow when he takes BCG intravesically? He is urinating currently every 30 min.
Do you think any lymph node involvement there? Do we need to do PET scan or whole body MRI to identify cancer /lymph node enlargement elsewhere in the body?
What are the things he need to follow when he takes BCG intravesically? He is urinating currently every 30 min.
Brief Answer:
Doesn't look like significant lymph nodes
Detailed Answer:
Lymph node spread and extravesical extension is possible only in muscle invasive disease. Here there's no muscle invasion.
The lymph nodes mentioned in the report are too small and may not be involved by disease.
The perivesical extension on CT may sometimes be due to inflammation around the tumor.
PET CT is not beneficial in this type of bladder cancer. MRI may be of some benefit but after TURBT it will show many inflammatory changes.
If in doubt, another cystoscopy and biopsy to rule out muscle invasive disease can be done.
Regards
Doesn't look like significant lymph nodes
Detailed Answer:
Lymph node spread and extravesical extension is possible only in muscle invasive disease. Here there's no muscle invasion.
The lymph nodes mentioned in the report are too small and may not be involved by disease.
The perivesical extension on CT may sometimes be due to inflammation around the tumor.
PET CT is not beneficial in this type of bladder cancer. MRI may be of some benefit but after TURBT it will show many inflammatory changes.
If in doubt, another cystoscopy and biopsy to rule out muscle invasive disease can be done.
Regards
Above answer was peer-reviewed by :
Dr. Vaishalee Punj

Brief Answer:
Doesn't look like significant lymph nodes
Detailed Answer:
Lymph node spread and extravesical extension is possible only in muscle invasive disease. Here there's no muscle invasion.
The lymph nodes mentioned in the report are too small and may not be involved by disease.
The perivesical extension on CT may sometimes be due to inflammation around the tumor.
PET CT is not beneficial in this type of bladder cancer. MRI may be of some benefit but after TURBT it will show many inflammatory changes.
If in doubt, another cystoscopy and biopsy to rule out muscle invasive disease can be done.
Regards
Doesn't look like significant lymph nodes
Detailed Answer:
Lymph node spread and extravesical extension is possible only in muscle invasive disease. Here there's no muscle invasion.
The lymph nodes mentioned in the report are too small and may not be involved by disease.
The perivesical extension on CT may sometimes be due to inflammation around the tumor.
PET CT is not beneficial in this type of bladder cancer. MRI may be of some benefit but after TURBT it will show many inflammatory changes.
If in doubt, another cystoscopy and biopsy to rule out muscle invasive disease can be done.
Regards
Above answer was peer-reviewed by :
Dr. Vaishalee Punj


Thank you so much for all your answer. It's so much beneficial.
What are the things he need to follow when he takes BCG intravesically? How long He has to hold the urine? He is urinating currently every 30 min.
What are the things he need to follow when he takes BCG intravesically? How long He has to hold the urine? He is urinating currently every 30 min.

Thank you so much for all your answer. It's so much beneficial.
What are the things he need to follow when he takes BCG intravesically? How long He has to hold the urine? He is urinating currently every 30 min.
What are the things he need to follow when he takes BCG intravesically? How long He has to hold the urine? He is urinating currently every 30 min.
Brief Answer:
2hr holding ideal
Detailed Answer:
Less fluid intake before the procedure. After injection, 2 hr holding recommended. After passing urine, more fluid intake.
2hr holding ideal
Detailed Answer:
Less fluid intake before the procedure. After injection, 2 hr holding recommended. After passing urine, more fluid intake.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar

Brief Answer:
2hr holding ideal
Detailed Answer:
Less fluid intake before the procedure. After injection, 2 hr holding recommended. After passing urine, more fluid intake.
2hr holding ideal
Detailed Answer:
Less fluid intake before the procedure. After injection, 2 hr holding recommended. After passing urine, more fluid intake.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar


Thank you. If he can't hold, will the medication be effective.

Thank you. If he can't hold, will the medication be effective.
Brief Answer:
partly effective
Detailed Answer:
Actually 30 min is too low. Hopefully it will improve by the time BCG is started.
partly effective
Detailed Answer:
Actually 30 min is too low. Hopefully it will improve by the time BCG is started.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar

Brief Answer:
partly effective
Detailed Answer:
Actually 30 min is too low. Hopefully it will improve by the time BCG is started.
partly effective
Detailed Answer:
Actually 30 min is too low. Hopefully it will improve by the time BCG is started.
Above answer was peer-reviewed by :
Dr. Chakravarthy Mazumdar


Doctor, I am so much worried that's why I am asking so much questions. He is still bleeding. Whether is it complication or disease progression. I sent you the picture of his urine. Please suggest what we need to do. Urologist did ultrasound to identify whether he has clot. Please provide your suggestion.

Doctor, I am so much worried that's why I am asking so much questions. He is still bleeding. Whether is it complication or disease progression. I sent you the picture of his urine. Please suggest what we need to do. Urologist did ultrasound to identify whether he has clot. Please provide your suggestion.
Brief Answer:
It seems clot is there
Detailed Answer:
I understand.
There seems to be clot in the urine. I hope bladder irrigation is going on. If the problem persists, another cystoscopy will be required.
Progression of disease so early after TURBT is possible but rare. So let's take it as a complication of TURBT for now.
It seems clot is there
Detailed Answer:
I understand.
There seems to be clot in the urine. I hope bladder irrigation is going on. If the problem persists, another cystoscopy will be required.
Progression of disease so early after TURBT is possible but rare. So let's take it as a complication of TURBT for now.
Above answer was peer-reviewed by :
Dr. Yogesh D

Brief Answer:
It seems clot is there
Detailed Answer:
I understand.
There seems to be clot in the urine. I hope bladder irrigation is going on. If the problem persists, another cystoscopy will be required.
Progression of disease so early after TURBT is possible but rare. So let's take it as a complication of TURBT for now.
It seems clot is there
Detailed Answer:
I understand.
There seems to be clot in the urine. I hope bladder irrigation is going on. If the problem persists, another cystoscopy will be required.
Progression of disease so early after TURBT is possible but rare. So let's take it as a complication of TURBT for now.
Above answer was peer-reviewed by :
Dr. Yogesh D


Thank you

Thank you
Brief Answer:
You are welcome
Detailed Answer:
If you don't have any more queries then please close this thread and give feedback.
Regards
You are welcome
Detailed Answer:
If you don't have any more queries then please close this thread and give feedback.
Regards
Above answer was peer-reviewed by :
Dr. Yogesh D

Brief Answer:
You are welcome
Detailed Answer:
If you don't have any more queries then please close this thread and give feedback.
Regards
You are welcome
Detailed Answer:
If you don't have any more queries then please close this thread and give feedback.
Regards
Above answer was peer-reviewed by :
Dr. Yogesh D


I don't have any questions now but if I need to ask any questions later, it will be easy for me if this thread is open. Since my brother is still in hospital and has symptoms.

I don't have any questions now but if I need to ask any questions later, it will be easy for me if this thread is open. Since my brother is still in hospital and has symptoms.
Brief Answer:
Ok
Detailed Answer:
sure
Ok
Detailed Answer:
sure
Note: For further queries related to kidney problems Click here.
Above answer was peer-reviewed by :
Dr. Kampana

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