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My Question Is What Are The Consequences Of Not Lowering My Ferritin In. 20-50?

Posted on Tue, 6 Aug 2024

Question: I had a blood test and result showed I carried two genes that classify me as being a. Hemochromatosis carrier. My doctor says my Ferritin level is high for a. Hemochromatosis.carrier and I need to have therapeutic phlebotomy to lower my ferritin. To 20-50. —. My question is what are the consequences of not lowering my ferritin in. 20-50????thanks..

Answered by Dr. Shailja Puri (5 hours later)

Brief Answer:
In absence of treatment hemachromatosis, iron will deposit in organs

Detailed Answer:
Hello,

Hemachromatosis is a hereditary condition wherein iron levels are high and iron gets deposited in soft tissues causing organ dysfunction.
In health, iron remains attached to hemoglobin and does not get deposited in any soft tissue.
The primary aim of treatment is to remove excess iron in body to prevent its deposition in soft tissues.
Phlebotomy removes blood from body and hence excess iron.
If the phlebotomy is not not permed, the excess iron will deposit in organs like liver, muscles, heart etc.
This will lead to organ dysfunction and if condition prevails for long, it can cause organ failure too.

If you have more queries, i will be glad to answer.
Thanks and take care
Dr Shailja Puri

Above answer was peer-reviewed by : Dr. Nagamani Ng

Follow up: Dr. Shailja Puri (34 hours later)

Thank you very much. I interested in knowing if current value is considered a little high, very high, extremely high for a person that Is Hemochromatosis.carrier.. currently, its running about 150 now .

Answered by Dr. Shailja Puri (55 minutes later)

Brief Answer:
Ferritin levels needs to maintained below 50

Detailed Answer:
Hello and welcome again,
Ferritin level of 150 is very high.
It needs to be lowered and ferritin needs to be maintained below 50.

Thanks and take care
Dr Shailja Puri

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Shailja Puri (1 hour later)

I just mage an appointment with hematologist. Its in. March. Can you provide any info on body symptoms with very high levels in a person with genetic dual gene issue? Does it deposit in the heart and what are the cardiac issues to he addressed? And , are there statistics on % of men with this problem.

Answered by Dr. Shailja Puri (13 hours later)

Brief Answer:
Deposition of iron in heart can lead to cardiac arrhythmias

Detailed Answer:
Hello and welcome again,
High levels of iron and ferritin in body can lead to deposition of iron in organs like heart, liver, skin etc.
Deposition of high levels of iron in heart muscles can lead to cardiac arrhythmias.
I suggest you to consult a cardiologist also for any cardiac problem.

Thanks and take care
Dr Shailja Puri
KINDLY HIT THANKS

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar

Follow up: Dr. Shailja Puri (12 hours later)

Thanks. I am so grateful for health care magic. I just saw my cardiologist. He never said anything, I will follow up

Follow up: Dr. Shailja Puri (0 minute later)

I just need to close out question.

Answered by Dr. Shailja Puri (8 hours later)

Brief Answer:
Thanks and take care

Detailed Answer:
Thanks and take care
Dr Shailja Puri

Note: Do you have more questions on diagnosis or treatment of blood disorders? Ask An Expert/ Specialist Now

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar