
My Sister Aged 50, Has Been Suffering From Peri Menopausal

From 2012 till now, upon the prescription of her gynaec she has taken the below medicines:
Regestrone-5mg
Trenexa-500mg
Sysran-N
Vegisil Cream
Primosa-1000mg
Ornida-500mg
Doxy 1-100mg
Danazol-100mg
Surfaz Ointment
Vagi tablets
Wellwoman
Fas3kit
Triben
Premain vaginal cream
Isoflav CR
Cetum-500mg
Flucon-150mg
Liviaz
Keto B cream
Neuroguard
2017 - she had started getting frequent spotting. Shen underwent DNC at that time for the complaint when her Endometrium thickness was 16mm. After the procedure, her symptoms subsided.
From next months onwards, periods were normal.
2018 - 6 to 8 months post DNC, frequent spotting started again. This continued from 2018 till 2019 XXXXXXX Normal periods and spotting post periods continued till XXXXXXX 2019.
2019 - From July 2019, there was no spotting periods for 4 months till Oct 2019. In November 2019 normal periods came, no periods since Dec 2019 only intermittent spotting.
2020 - Since XXXXXXX symptoms increased with lower back and abdomen pain. Gynaec took Ultrasound scan, PAP smear and FSH.
FSH=27;
Endometrium thickness=8
PAP smear=Normal
From Aug this year, severe burning sensation in pelvic down the toe. Burning near feet and vaginal area. Light burning near chin. Symptoms of overheat.
Gynaec suggested Clingen, Doxycyclin 100mg suspecting infection along with Cyclopam. She gave Pause MF for 5 days. Flow reduced but spotting continued.
Now,
spotting is minimum,
pain reduced,
only burning sensation and overheat.
No relief from home remedies. Soya milk & Toto Woman was advised but symptoms didn’t reduced.
Below are my questions:
1. Are these symptoms anything to be concerned about?
2. How long will these symptoms last?
3. Pls advise on how to manage severe unbearable burning sensation and heat in the body.
peri- menopausal status
Detailed Answer:
Hello,
She is definitely in her perimenopausal status characterised by hot flushes , vaginal dryness often accompanied with joint pains, mood swings, burning sensation in hands and feet. The concern here is the irregular shedding which is again commonly seen in perimenopausal age group. This can be controlled with antifibrinolytics and also if required cyclical progesterones if required depending on the histopathology report of the endometrial biopsy following d&c procedure.
Ideally she has to be on estradiol supplementation with calcium and vit d3 supplementation with multivitamins and minerals with isoflavones.
The bleeding per vaginum - if endometrial biopsy is normal then she can be placed on low dose oral contraceptive hormonal pills for next 3 cycles to alleviate these symptoms.
Also important is to use only alkaline vaginal washes for local cleansing and to avoid use of local soaps or shower gels over genital region to avoid vaginal dryness and infections.
Regards

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