Brief Answer:
Alcohol and Cymbalta may cause liver damage.

Detailed Answer:
Hi,
Thanks for writing in to us.

I have read through your query in detail.

Talk to your doctor before using Cymbalta (Duloxetine) together with alcohol. Duloxetine may cause liver damage, and taking it with alcohol may increase that risk. You should avoid or limit the use of alcohol while being treated with Duloxetine. Call your doctor immediately if you have fever, chills, joint pain or swelling, excessive tiredness or weakness, unusual bleeding or bruising, skin rash or itching, loss of appetite, nausea, vomiting, dark colored urine, or yellowing of the skin or the whites of your eyes, as these may be symptoms of liver damage. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Hope your query is answered.
Do write back if you have queries.

Dr.A.Rao Kavoor

---