Question: Hi,
I've been vomiting every day, all day for almost 3 months now and no specialists have been able to pin it down as my results of GI, OBGYN, NEURO, ENT, PULM, CARDIO, ENDO, have roughly been unremarkable enough to suggest what is happening to me. I have shown dry flushing and other problems suggestive of carcinoid syndrome, but those tests have been negative (even low). My hypothyroid became dangerously overactive-TSH at a .06, but with an alteration of medication, it is now normal and I am still having these symptoms. I had low cortisol, but with the ACTH stimulation test, it showed I did not have adrenal insufficiency. ANA 1:320. MRI (brain) and CT (neck) have shown mild acute sphenoid sinusitis, mild-moderate right internal laryngocele and mild left internal laryngocele at the level of thyrohyoid ligaments and multiple, non-enlarged, non necrotic, mildly enhancing, cervical, supraclavicular, upper mediastinal and partially seen axillary lymph nodes (that RADIO are suggesting are likely benign and reactive). Also, an ENT scope showed "cobblestoning" which was not present during an Endoscopy (2 mos. prior).

Symptoms for entire illness: Vomiting, Hoarseness, Migraines with eye and jaw pain and blurry vision, Tolerable to stabbing abdominal pain, Diarrhea (blood for 2 wks (after clear colonoscopy and pill endoscopy) and found in rectal exam), Fever and chills, Chest Pain (not persistent, dull to sharp), Difficultly swallowing (beginning of illness and recently recurring (3 wks)), Labored upper airway breathing/shortness of breath with minimal tracheal wheezing, tightness, and mild dry cough (beginning of illness and recently recurring (3 wks)), Raised BP and HR (HR has gone up to over 120 resting and BP has gone over 150 resting- normal 102-108 BP, HR has been around 100), Night Sweats, Dry Flushing (Face, Chest, Upper Arms, Upper Legs), Bloody nose, Significant joint and random sharp muscle pain, Abdominal dissension, Skin itching and pigmentation changes, and Swollen lymph nodes (one to size of egg and has decreased). I have Celiac Disease, Asthma, Allergies, Hypothyroidism, Endometriosis, and Mild Rheumatoid Arthritis. I follow a plant-based diet and am strictly gluten free. It took most of my life before the Celiac was diagnosed because I was somehow gaining weight despite diet, exercise, and active lifestyle (when well) and consistently showing healthy pathology- during the Endoscopy, my villi were completely eroded and my biopsies were highly positive- I'm difficult to diagnose because my body works this way- complicated.

After the CT neck results, should I still push for biopsies of the swollen and firm, but 1cm and less, lymph nodes, just in case? Is it possible for the sphenoid sinusitis to cause a pituitary disorder that may be causing the abnormal hormone levels and problems? Is it possible to have carcinoid syndrome or some other type of cancer that is not showing up clearly? Can my diet be fighting whatever is happening to me and keeping these results from strongly showing up? I'm hoping someone else may notice something or anything at all as I am getting desperate and beyond ready to get well and back to my life.

Thank you!