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Suggest A Diet Plan While Experiencing Elevated Potassium, Blood Sugar, Persistently Elevated Serum Calcium, Excessive Thirst And Low Vitamin D Level

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Posted on Fri, 8 Jan 2021
Question: I followed your advice last Tues. and went to prompt care to see a doctor who told me to stop taking the Fosamax . I only toook it for 4 weeks,and my last day was May 11. The following blood tests were done:25 Hydroxy VitaminD, CBC differential, Comprehensive metabolic panel, TSH, and Vitamin b12. I had avoided vitamin D foods for most part for 3 and half weeks because after taking 1000 IU on both a Wed. and Fri., I had severe thirst and shaky fatigue. About every four days when my thirst seemed better, I would eat an egg of a small portion of catfish, my super-excessive thirst would come back. The NP I had seen at start of this saga had prescribed the once a week fosamax and 2000 daily to help with recently diagnosed osteoporosis and my vitamin D level was only 20. So this morning I got results back. Most thigs were normal, but my glucose level was 104. my potassium was 5.3 (the last 2 weeks baked potatoes have tasted like gourmet food) and after avoiding vitamin D for all but 4 days in a 3 and half week period, my vitamin D level was 19 when it had been 20 4 weeks ago when my calcium level had been 10.6 a month ago and is now 11.3. I thought I should eat something with Vitamin D and ate an egg. Within an hour, that horrible intense thirst came back, and I have been drinking water nonstop, and of course it is interfering with my appetite. I am trying to figure out what to eat until my doctor appointment in a week. P.S. The doctor from the prompt care just called me to say my kidney and liver are functioning just fine,and he even went back to see online records that show in 2014 my calcium level was 11.4, so it has been holding steady for 4 years, and probably not causing the thirst issue. Have any ideas of what I should be eating while I wait week and half to see my soon to be GP?

I am guessing that maybe the premarin cream is involved in my excessive thirst.I just looked at the pamphlet again that came with it. It does say to consult Dr. if blood calcium is high. I started it mid March before I got the bone density scan results.
doctor
Answered by Dr. Bonnie Berger-Durnbaugh (2 hours later)
Brief Answer:
Thoughts on this

Detailed Answer:
Hello -

I did not realize you were taking Fosamax. That wasn't part of the last question so I didn't know.

So looking at what has happened you have:
Elevated potassium
Slightly elevated blood sugar (non-fasting?)
Persistently elevated serum calcium
Excessive thirst
Low Vit. D

The elevated potassium is unlikely to be related to potassium from food as research shows normal kidneys have no trouble getting rid of that.

It's possible the elevated potassium was due to the technique of the person who handled it. This is because if red blood cells break during the transferring/handling of the specimen, potassium that is inside the cells spills out giving a false reading.

But elevated potassium could be due to other problems so it bears checking potassium level.

Your excessive thirst could be from the continued elevation in calcium. I think this is much more likely than from your minimally elevated blood sugar (which isn't particularly elevated if you were not fasting when it was drawn).

I really doubt that the premarin cream is causing the problem. It does not enter the system in amounts that oral premarin does, and the pamphlet side effect information is based on systemic premarin.

At this point what I recommend is:
1. Call the nurse practitioner and request the PTH test as well as 24 hour urine calcium test. The later requires a special container. The cause of your hypercalcemia needs to be sorted out ASAP. When you have your blood draw, your potassium should be rechecked, and I'd get an A1C if that blood sugar was not done fasting. Don't wait until you are seen by the doctor - get these tests done now so you will be able to move forward when you see him/her.

So ask for:
-PTH test
-24 hour urine calcium
-repeat potassium (to see if it was a lab error)
- possibly A1C

Other things to consider are adrenal insufficiency, but you have not detailed symptoms consistent with that.

Now to answer your question of what to eat:
That depends entirely on what the underlying cause is so that needs to be sorted out. I recommend a general healthy balanced diet until we know what the cause of the thirst and hypercalcemia are due to. Don't eat excessive amounts of any one particular thing:

Complex carbohydrates such as whole grains (basmati brown rice, etc), wide range of vegetables and fruits, chicken, turkey, lean meat, fish (as tolerated).

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Bonnie Berger-Durnbaugh (1 hour later)
Sorry I was waiting for new email and did not realized you had responded. I am now with a different network after the prompt care visit so I will not go back to NP. There has to be a reason why I only get super-excessively thirsty when I ingest vitamin D. The Premarin does say to consult Dr. if blood calcium is high but doesn't say why. I do not know if I can contact new Dr. to ask nursing staff to run tests before I see him.

P.S. I have been researching diabetes insipidus and it has so many causes but I do seem to have the symptoms.
doctor
Answered by Dr. Bonnie Berger-Durnbaugh (36 minutes later)
Brief Answer:
Thoughts on this

Detailed Answer:
Diabetes insipidus is a possibility, but given that you have elevated calcium, I would look to that first, to sort out the reason for it. Elevated calcium can cause excessive thirst.

If the premarin is topical for intravaginal use, it would not be expected to increase serum calcium.


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Bonnie Berger-Durnbaugh (32 minutes later)
I just found this when researching Premarin... "To make sure you can use vaginal conjugated estrogens tell your doctor if you have... high or low levels of calcium...porphyria..." I did not know I had the first during my gyn. appointment and now I have the second. So I am guessing the manufactures know there are problems with these 2 conditions and their medicine. Now I want to know how long Premarin cream remains in your system after discontinuing use and what problems patients taking this drug with those 2 conditions have.
doctor
Answered by Dr. Bonnie Berger-Durnbaugh (4 hours later)
Brief Answer:
Thoughts on this

Detailed Answer:
Hello -

Yes, sorry for the wait.

In doing a little research on the subject, I found this older article which states that estrogen increases calcium absorption via it's effect on vitamin D. But as your vitamin D level is actually rather low, I would not expect this to be the reason for the elevated serum calcium levels you have been having.

https://XXXX.com/0000

I also found this general article/guidelines about hypercalcemia:

https://www.XXXX.org/0000.html

And here is an article regarding the relationship of taking estrogen with a type of porphyria:

http://www.XXX.com/XXXX

I found some very old articles speculating on the mechanisms by which estrogen may precipitate porphyria cutanea tarda, but as you aren't having sun sensitive blistering, I don't think it is an issue for you.


Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
doctor
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Follow up: Dr. Bonnie Berger-Durnbaugh (18 hours later)
Thanks for your response. I mistakenly put porphyria i my question because I was tired and confused it with something else. So sorry. I just get extremely thirsty with any intake of Vitamin D, ad then end up urinating every half hour and start next day with diarrhea. So not concentrating well. Thanks for your help.
doctor
Answered by Dr. Bonnie Berger-Durnbaugh (1 hour later)
Brief Answer:
Thoughts on this

Detailed Answer:
Do you have diarrhea when you don't take the Vitamin D supplement?

And when did the excessive thirst start relative to the meds you've been taking and abnormal labs (the premarin cream, and elevated calcium)?
Note: For more detailed guidance, please consult an Internal Medicine Specialist, with your latest reports. Click here..

Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Bonnie Berger-Durnbaugh

General & Family Physician

Practicing since :1991

Answered : 3133 Questions

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Suggest A Diet Plan While Experiencing Elevated Potassium, Blood Sugar, Persistently Elevated Serum Calcium, Excessive Thirst And Low Vitamin D Level

Brief Answer: Thoughts on this Detailed Answer: Hello - I did not realize you were taking Fosamax. That wasn't part of the last question so I didn't know. So looking at what has happened you have: Elevated potassium Slightly elevated blood sugar (non-fasting?) Persistently elevated serum calcium Excessive thirst Low Vit. D The elevated potassium is unlikely to be related to potassium from food as research shows normal kidneys have no trouble getting rid of that. It's possible the elevated potassium was due to the technique of the person who handled it. This is because if red blood cells break during the transferring/handling of the specimen, potassium that is inside the cells spills out giving a false reading. But elevated potassium could be due to other problems so it bears checking potassium level. Your excessive thirst could be from the continued elevation in calcium. I think this is much more likely than from your minimally elevated blood sugar (which isn't particularly elevated if you were not fasting when it was drawn). I really doubt that the premarin cream is causing the problem. It does not enter the system in amounts that oral premarin does, and the pamphlet side effect information is based on systemic premarin. At this point what I recommend is: 1. Call the nurse practitioner and request the PTH test as well as 24 hour urine calcium test. The later requires a special container. The cause of your hypercalcemia needs to be sorted out ASAP. When you have your blood draw, your potassium should be rechecked, and I'd get an A1C if that blood sugar was not done fasting. Don't wait until you are seen by the doctor - get these tests done now so you will be able to move forward when you see him/her. So ask for: -PTH test -24 hour urine calcium -repeat potassium (to see if it was a lab error) - possibly A1C Other things to consider are adrenal insufficiency, but you have not detailed symptoms consistent with that. Now to answer your question of what to eat: That depends entirely on what the underlying cause is so that needs to be sorted out. I recommend a general healthy balanced diet until we know what the cause of the thirst and hypercalcemia are due to. Don't eat excessive amounts of any one particular thing: Complex carbohydrates such as whole grains (basmati brown rice, etc), wide range of vegetables and fruits, chicken, turkey, lean meat, fish (as tolerated).