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Suggest An Alternative Medication For Acebrophylline

Posted on Fri, 28 Apr 2023

Question: Hi,

My father is a NSIP patient, who is being treated by a doctor from Apollo XXXXXXX We live in XXXXXXX Doctor from XXXXXXX prescribed a medicine called 'Pulmoclear':
https://www.0XoXXX.com/drugs/XXXX-0000

This drug unfortunately not available in our country. And the stock we had for my father has ended. We are going back to XXXXXXX on 2nd April for revisit and we do not have any other option to take medicine in between.

We have Acetylcysteine tablets, but we do not have 'Acebrophylline (100mg)' in our country. Any suggestion that could be used for next 2 weeks in place of the above medicine? Montelukast may be? My father has been taking this medicine for 6 months.

Answered by Dr. Drkaushal85 (20 minutes later)

Brief Answer:
No, montelukast is not substitute for acebrophyllin.

Detailed Answer:

Hello,

Pulmoclear has a combination of Acebrophyllin and N Acetyl Cystine.
Acebrophyllin is a bronchodilator drug. Montelukast is anti allergic drug so montelukast is not a substitute for Acebrophyllin.

You can search for Deriphyllin tablet or Doxophyllin tablet as a substitute for Acebrophyllin. These are of the same Xanthin group of bronchodilators.

Hope I have solved your query. I will be happy to help you further. Wishing good health to your father. Thanks.

Regards,
Dr. Kaushal Bhavsar
Pulmonologist

Above answer was peer-reviewed by : Dr. Kampana

Follow up: Dr. Drkaushal85 (54 minutes later)

Hi, Thanks for your reply. This drug seems to be available in our country:

http://www.inceptapharma.com/view-product.php?pid=554

While deriphyllin combination isn't available, rather only Theophylline is available. Please advise the proper dose to replace acebrophyllin 100mg with doxophyllin. Thanks a lot for your reply.

Answered by Dr. Drkaushal85 (5 minutes later)

Brief Answer:
Give him theophylline 100mg and acetyl cystine 600mg

Detailed Answer:
Thanks for your follow up question on Healthcare Magic.
I can understand your concern.
Theophylline 100mg will be sufficient.
So give him theophylline 100mg and acetyl cystine 600mg.
Hope I have solved your query. If you are not having further queries, then please close the conversation and rate my answer.
You can ask me directly on bit.ly/askdrkaushalbhavsar. Wishing good health to your father. Thanks.

Above answer was peer-reviewed by : Dr. Remy Koshy

Follow up: Dr. Drkaushal85 (10 minutes later)

Hello Doctor, Thanks a lot for your advise. The have 200mg sustained release tablets instead of 100mg instant release:

http://www.XXXX.com/view-product.XXXX=0000

Seems alright? Sorry for pushing a lot here. Thanks.

Answered by Dr. Drkaushal85 (4 minutes later)

Brief Answer:
What is his weight?

Detailed Answer:

Hello,

Actually Theophylline has dosage according to the weight of the patient.
So please let me know:
1. His weight
2. Is he having any illnesses like hypertension, diabetes?

Please reply me answers of above asked questions, so that I can guide you better. I will be happy to help you further. Wishing good health to your father. Thanks.

Regards,
Dr. Kaushal Bhavsar
Pulmonologist

Above answer was peer-reviewed by : Dr. Kampana

Follow up: Dr. Drkaushal85 (11 minutes later)

Hi, Thanks.

He is 5 feet, weight around 48KG, and he has hypertension, but no diabetes. Thanks.

Answered by Dr. Drkaushal85 (2 minutes later)

Brief Answer:
Give him half tablet of 200mg sustained release.

Detailed Answer:

Hello,

Theophylline dose for him would be 100mg. If you have 200mg SR (sustained release) tablets then give half the tablet.

Hope I have solved your query. If you are not having further queries, then please close the conversation and rate my answer. Wishing good health to your father. Thanks.

Regards,
Dr. Kaushal Bhavsar
Pulmonologist

Above answer was peer-reviewed by : Dr. Remy Koshy

Follow up: Dr. Drkaushal85 (2 days later)

Hi, Thanks for your advise. Can you please if NSIP patients travel over flights? Do they need extra oxygens?

Answered by Dr. Drkaushal85 (21 minutes later)

Brief Answer:
Yes, they can definitely travel by flight.

Detailed Answer:

Hello,

If he is not having breathlessness on rest or maintaining oxygen saturation then he can definitely travel by flight.
So please let me know:
1. Is he having breathlessness?
2. Is he maintaining oxygen saturation at rest?

Please reply me answers of above asked questions, so that I can guide you better. I will be happy to help you further. Wishing good health to your father. Thanks.

Regards,
Dr. Kaushal Bhavsar
Pulmonologist

Above answer was peer-reviewed by : Dr. Nagamani Ng

Follow up: Dr. Drkaushal85 (40 minutes later)

He feels some chest pain when he walks up more than 2nd floor using stairs. He doesn't feel any breathless on normal walking. We have never calculated his normal oxygen saturation level, but he never needed any additional oxygen. Thanks a lot Doctor, hope we will visit your clinic someday :)

Answered by Dr. Drkaushal85 (1 hour later)

Brief Answer:
I don't think he will need oxygen.

Detailed Answer:

Hello,

Well, I don't think he will need oxygen in flight.

Hope I have solved your query. Wishing good health to your father. Thanks.

Regards,
Dr. Kaushal Bhavsar
Pulmonologist

Above answer was peer-reviewed by : Dr. Nagamani Ng