
Suggest The Ideal Dosage For MS Contin

first there are a dozen other meds
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for RLS that are pretty close to non-toxic. Every Parkinson's medication and every muscle relaxant can work on RLS and are not dangerous.
Second, the units are not the usual. MSContin comes in amount not volume (milligram, not milliliter). 10 mg is lower than the usually given lowest dose (15). Ordine comes in a TEN FOLD RANGE OF DOSE! This is the highest range of almost any medicine. Similar to saying have a glass of water and that meaning anything from a dixie cup to a 2 liter bottle!
Narcotics can all be overdosed. They have a much higher safety range than other common drugs such as tylenol (5 fold), water (10 fold), oxygen (5 fold). 1 gm of tylenol is the usual extra strength, 5 gram is likely to injure the liver. 1 gallon of water is reasonable, I have had a patient have seizures from 5 gallons.
60 mg of morphine while not fatal is getting to be somewhat high. 10 mg is somewhat low. at 10 mg, I'm not sure other than allergy whether there could even be problems including addiction or withdrawal. 10 mg is quite safe; frankly compared to over the counter aspirin. Ordine is the same stuff and the same range of amount applies BUT it is PER MILLILITER (volume) so, the lowest dose 1 mg is FIVE mg if 5 Milliliter is given (one teaspoon). So, multiply all the ORDINE NUMBERS BY FIVE and that is the teaspoon dose. The ordine 2 is 10 mg per teaspoon. 10 mg is not that much. 100 mg is a lot but PROBABLY not fatal. That is the dose at ONE time not Per Day. So, a ten milligram pill once a day for a month is 300 mg, this is entirely safe since it is spread out over a month and it wears off each day (or less). Ordine wears off in about 6 hrs (or less).
If you take one long acting morphine twice a day (20 mg) and 10 mg of ordine 3 times a day (2 mg becomes 10 with one full teaspoon). that is 50 mg in one day. This is an AVERAGE dose. There is some danger of becoming addicted and dependent to it at the average dose. 100 to 200 is dangerous. That would be TEN to TWENTY of the MSCONTIN (10 fold) or TWO TO FOUR teaspoons of the highest dose of the ordine but TWENTY TO FORTY teaspoons of the lowest dose ordine.
1) make sure you know what is in the ordine
2) consider having an overdose rescue pen antidote around
3) also consider a NON-NARCOTIC drug for RLS.
Nobody uses narcotics for RLS.


Non-narcotics.
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Ok, let us start TODAY with a magnesium supplement. It has some muscle relaxant effects. Someone with muscle cramps should be checked for electrolytes. Given the symptoms are constant, while the electrolytes vary, unless someone has a (REALLY RARE) electrolyte losing genetic condition and the condition started by teens and ....yeah, you don't have that. But magnesium is often helpful even if the level of magnesium isn't low. You need to NOT have kidney failure or the magnesium level can go too high. The degree of kidney failure would mean you would have a LOT of other problems (but not leg cramps). You don't have the kidney failure; magnesium at levels between 100 mg to 400 mg a day can be helpful.
Muscle relaxants. Robaxin and flexeril or baclofen. They need supervision.
Parkinson's drugs. Requip is the main one used; sifrol is a more expensive version of it--similar chemistry and action but a different role of the dice for reactions. Sinemet is an alternative that is somewhat dangerous in parkinson's disease and is generally not used.
Amitryptiline. Under a doctor's supervision.


There's the medicine and the reaction
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Morphine generally wears off on its effects in 6 hours. Long acting preparations might be up to entire day longer
But, the reaction to the medicine is a very different story depending on the type of reaction. A plain allergy (hives, very common with morphine and not necessarily an allergy, morphine just causes hives) is a bit longer than the time for the drug to be gone and 3 to 5 days but an anti-histamine would work on it very soon like in 1 day. Withdrawal from morphine takes about 2 weeks to mostly be gone.

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