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Suggest Treatment For FVL Thrombophilia

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Posted on Mon, 21 Dec 2015
Twitter Tue, 22 Dec 2015 Answered on
Twitter Mon, 11 Jan 2016 Last reviewed on
Question : Best medications for factor 5 leiden heterozygous for healthy 44 year old male.
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Answered by Dr. Diptanshu Das (5 hours later)
Brief Answer:
Not all people with this condition require treatment

Detailed Answer:
Thanks for asking on Health care magic.

Factor V Leiden is an autosomal dominant genetic condition which indicates that it can get expressed in heterozygous condition. However, it exhibits incomplete penetrance, i.e. not every person who has the mutation develops the disease. Hence treatment depends on the intensity of your symptoms. If genetic tests have confirmed that you have factor V Leiden, but you have not exhibited any blood clots, then you probably do not need blood thinners on a regular basis. If you have blood clots, low molecular injectable heparins like enoxaparin (Lovenox) and dalteparin (Fragmin) are good choces. However, newer oral blood thinners like Dabigatran (Pradaxa) Rivaroxaban (Xarelto) and Apixaban (Eliquis) are now available and may be considered best choice.

Regards
Above answer was peer-reviewed by : Dr. Chakravarthy Mazumdar
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Answered by
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Dr. Diptanshu Das

Pediatrician

Practicing since :2005

Answered : 3879 Questions

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Suggest Treatment For FVL Thrombophilia

Brief Answer: Not all people with this condition require treatment Detailed Answer: Thanks for asking on Health care magic. Factor V Leiden is an autosomal dominant genetic condition which indicates that it can get expressed in heterozygous condition. However, it exhibits incomplete penetrance, i.e. not every person who has the mutation develops the disease. Hence treatment depends on the intensity of your symptoms. If genetic tests have confirmed that you have factor V Leiden, but you have not exhibited any blood clots, then you probably do not need blood thinners on a regular basis. If you have blood clots, low molecular injectable heparins like enoxaparin (Lovenox) and dalteparin (Fragmin) are good choces. However, newer oral blood thinners like Dabigatran (Pradaxa) Rivaroxaban (Xarelto) and Apixaban (Eliquis) are now available and may be considered best choice. Regards