Suggest Treatment For Dysphonia And Discoordination In The Muscles

Posted on Sat, 14 Jul 2018

Medically reviewed by Ask A Doctor - 24x7 Medical Review Team

Sat, 14 Jul 2018 Answered on

Wed, 3 Aug 2022 Last reviewed on

Question : I’ve been under investigation for dysphagia for two years; I’ve also developed some dysphonia in the past year or so. I’ve had many tests, most of them showing some discoordination in the muscles used for swallowing, but they can’t pinpoint a pattern that would lead to a specific diagnosis (like achalasia). I recently had a blood test for acetylcholine receptor antibodies, and the result popped up online, but I have not been contacted by my doctor yet. The result was <.20. Could you please help me interpret that? Thank you.

Answered by Dr. Mirjeta Guni (6 hours later)

Brief Answer:
About acethylcholine antibodies

Detailed Answer:

Hello,

Myasthenia Gravis is one of the pathologies that causes dysphagia due to the presence of acethylcholine antibodies (binding or blocking antibodies) that block the effect of this neurotransmitter and as a result the muscles do not contract normally.
The result you reported means that the antibodies are negative, when they result over 0.5 nMol/ L are considered positive.
So, myasthenia is excluded as a cause of the dysphagia.

Hope the information will help.
Regards,
Dr. Mirjeta

Above answer was peer-reviewed by : Dr. Yogesh D