Brief Answer: Nothing to worry. Detailed Answer: Hi, Welcome to HCM. Chance of pregnancy with each cycle if everything is fine (Normal semen, regular ovulation & patent tubes) is 25-30%, which stands for 85-90% chance with one year of unprotected intercourse. As you said, wife's ovulation is regular, other two things need evaluation. Out of the two semen analysis is non invasive & can be done easily. You can get it done (if not already done) from any standard lab. Regarding wife's tubes; if she had no past history suggestive of pelvic infection (like fever with lower abdominal pain & foul smelling vaginal discharge), she need not undergo any tubal test right now. You can do it if she doesn't conceive in 9-12 months. Coming to tips to increase chance of conception, one golden rule is to have regular sexual intercourse at least 2-3 times a week (excluding during menses) irrespective of fertile period & to have it daily if possible during fertile period (that is from day 10 to day18 of menstrual cycle if cycle is of 28-30 days: The day menses start is counted as day one). This reduces anxiety, as anxiety to conceive itself can reduce fertility & reduce chance of conception. If ovulation is confirmed to be happening regularly in one/two cycles, no need to go on repeating tests (OPKs) to time intercourse, as it increases anxiety, reduces performance & reduces fertility. So in summary, you need only one test (If wife doesn't have history suggestive of pelvic infection): semen analysis. As you both are young, pregnancy should happen easily if semen analysis comes normal. The medicines you & your wife are taking are not likely to affect fertility, no need to worry for that. Hope this helps you. Let me know if you have other concerns. Regards.

---