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Suggest Treatment For Itching Duee To Skin Allergey And Eosinophilia

Posted on Tue, 2 Dec 2014

Question: Hi my absoulute eosinophil count is 1050cells/cumm. And also i facing skin allergey , itching on face and body
Please suggest how to reduce AEC level. I am apply topcort rt ointment and dermodew soaps .

Answered by Dr. Tushar Kanti Biswas (2 hours later)

Brief Answer:
Skin allergey and eosinophilia

Detailed Answer:
Hi,

Thank you for your query. I can understand your concerns.

Low- to mid-potency topical glucocorticoids are employed in most treatment regimens for skin allergy or atopic dermatitis(AD). Low-potency topical glucocorticoids should be selected for use on the face to minimize the risk of skin atrophy.

Topcort ointment (Mometasone 0.1%) and Topicort Cream/Ointment (0.25%Desoximetasone) both are potent topical glucocorticoids.
Allergies such eczema, AD are associated with eosinophilia.
Treatment with systemic glucocorticoids (prednisolone) will reduce AEC level but their use should be limited to severe exacerbations of AD unresponsive to topical therapy.

Regards

Dr. T.K. Biswas M.D. XXXXXXX

Above answer was peer-reviewed by : Dr. Vaishalee Punj

Follow up: Dr. Tushar Kanti Biswas (6 hours later)

Thanks for your reply But the itching and hardness is also expend to hands, legs ,back and other part of the body also, since from last two months is aggravated too, I have few clarifications is as follow.
1) Any other medicine is required for decrease AEC level ? If continue the TOPCORT in long-term, Is it any other side effects?
2) How to avoid this skin allergy permanently? Some time, I was facing cold allergies also.

And also since from two years I have take medicine for BP and diabetic. But it is under control. I here with attached a recent total Blood testing reports and when my allergy has aggravated time my face photo.
Hence please suggest about corrective and preventive medicines for my above problems

Answered by Dr. Tushar Kanti Biswas (54 minutes later)

Brief Answer:
eosinophilia,skin allergy ,

Detailed Answer:
Hi,

1.IL-5(Interleukin) is the dominant eosinophil growth factor, and can be specifically inhibited with the monoclonal antibody mepolizumab but you need specialist consultation for that.
2.Avoidance of cutaneous irritants, adequate moisturizing through the application of emollients, judicious use of topical anti-inflammatory agents, and prompt treatment of secondary infection.
To bathe no more often than daily, using warm or cool water, and to use only mild bath soap.
Immediately after bathing, while the skin is still moist, a topical anti-inflammatory agent in a cream or ointment base should be applied to areas of dermatitis, and all other skin areas should be lubricated with a moisturizer.
Approximately 30 g of a topical agent is required to cover the entire body surface of an average adult.
Two nonglucocorticoid anti-inflammatory agents are available: tacrolimus ointment and pimecrolimus cream.
Antihistamines are most often used to control pruritus, and mild sedation may be responsible for their antipruritic action.
TOPCORT long-term side effects:
Skin atrophy and the potential for systemic absorption are constant concerns, especially with more potent agents,as it may offset control of your diabetes.
Thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)

Regards

Dr. T.K. Biswas M.D. XXXXXXX

Above answer was peer-reviewed by : Dr. Raju A.T

Follow up: Dr. Tushar Kanti Biswas (8 hours later)

Dear sir ,

Thanks for your immediate answers, as per your suggestions, specialist consultant is required,to avoid secondary infections. Please advise me few clarifications is as below.
•Can I consult dermatologist or physician? Can you refer any specialist doctor in Bangalore?
•Can I start apply tacrolimus ointment and pimecrolimus cream? If I use continuously ,it would any side effects in future?
Since from few days back , i start consult with Homeopathy medicine in Batra, Is It feasible ? please advice.
• To reduce AEC level in my blood, any internal medicine like tablets or drugs are required ? Please suggest any such medicine.
Regards XXXXXXX XXXXXXX

Answered by Dr. Tushar Kanti Biswas (9 hours later)

Brief Answer:
Skin allergy & high AEC

Detailed Answer:
Hi,

Thank you for your query. I can understand your concerns.
Since your basic ailment is allergic dermatitis(AD), you should see a dermatologist.

http://doctor.healthcaremagic.com/doctors/Dermatologists-in-Karnataka/L18885S9

I am unable to give any reference of any specialist doctor in this regard in Bengaluru.
I have given a link which contains list dermatologists in XXXXXXX
You can use non-glucocorticoid anti-inflammatory agents like tacrolimus ointment and pimecrolimus cream. These agents are macrolide immunosuppressants for topical use in AD and these agents do not cause skin atrophy, nor do they suppress the hypothalamic-pituitary-adrenal axis.However, concerns have emerged regarding the potential for lymphomas in patients treated with these agents. Hence caveat about long-term use.
I am unable to comment on efficacy of Homeopathy.
Treatment with a short course of systemic glucocorticoids (prednisolone) for 7-10 days will reduce AEC level.

Regards

Dr. T.K. Biswas M.D. XXXXXXX

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Above answer was peer-reviewed by : Dr. Bhagyalaxmi Nalaparaju